Idiopathic hypereosinophilic syndrome (HES) is a rare disease characterized by tissue involvement and organ dysfunction due to abnormal eosinophil proliferation. Evolution of HES into myeloid or T-cell malignancies has been frequently reported. Here, we describe a case of HES that preceded the occurrence of a high-grade B-lymphoblastic lymphoma in which clonal evolution has been demonstrated at the molecular level.

Rapanotti, M., Caruso, R., Bernardini, S., Coletti, V., LO COCO, F., De Rossi, G. (2005). Idiopathic hypereosinophilic syndrome: A case evolving in B-lymphoblastic lymphoma. LEUKEMIA RESEARCH, 29(8), 975-979 [10.1016/j.leukres.2005.01.010].

Idiopathic hypereosinophilic syndrome: A case evolving in B-lymphoblastic lymphoma

CARUSO, ROBERTA;Bernardini, S;LO COCO, FRANCESCO;
2005-01-01

Abstract

Idiopathic hypereosinophilic syndrome (HES) is a rare disease characterized by tissue involvement and organ dysfunction due to abnormal eosinophil proliferation. Evolution of HES into myeloid or T-cell malignancies has been frequently reported. Here, we describe a case of HES that preceded the occurrence of a high-grade B-lymphoblastic lymphoma in which clonal evolution has been demonstrated at the molecular level.
2005
Pubblicato
Rilevanza internazionale
Articolo
Esperti anonimi
Settore MED/15 - MALATTIE DEL SANGUE
English
Humans; Hypereosinophilic Syndrome; Infant; Lymphoma, B-Cell; Oncogene Proteins, Fusion; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction; Reverse Transcriptase Polymerase Chain Reaction; Transcription, Genetic
Rapanotti, M., Caruso, R., Bernardini, S., Coletti, V., LO COCO, F., De Rossi, G. (2005). Idiopathic hypereosinophilic syndrome: A case evolving in B-lymphoblastic lymphoma. LEUKEMIA RESEARCH, 29(8), 975-979 [10.1016/j.leukres.2005.01.010].
Rapanotti, M; Caruso, R; Bernardini, S; Coletti, V; LO COCO, F; De Rossi, G
Articolo su rivista
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/162103
Citazioni
  • ???jsp.display-item.citation.pmc??? 2
  • Scopus 11
  • ???jsp.display-item.citation.isi??? 12
social impact