Brain-derived neurotrophic factor (BDNF) gene variants may potentially influence behaviour. In order to test this hypothesis, we investigated the relationship between BDNF Val66Met polymorphism and aggressive behaviour in a population of schizophrenic patients. Our results showed that increased number of BDNF Met alleles was associated with increased aggressive behaviour.

Spalletta, G., Morris, D., Angelucci, F., Rubino, I., Spoletini, I., Bria, P., et al. (2010). BDNF Val66Met polymorphism is associated with aggressive behavior in schizophrenia. EUROPEAN PSYCHIATRY, 25(6), 311-313.

BDNF Val66Met polymorphism is associated with aggressive behavior in schizophrenia

RUBINO, IVO;SIRACUSANO, ALBERTO;BERNARDINI, SERGIO;CALTAGIRONE, CARLO;
2010-10-01

Abstract

Brain-derived neurotrophic factor (BDNF) gene variants may potentially influence behaviour. In order to test this hypothesis, we investigated the relationship between BDNF Val66Met polymorphism and aggressive behaviour in a population of schizophrenic patients. Our results showed that increased number of BDNF Met alleles was associated with increased aggressive behaviour.
ott-2010
Pubblicato
Rilevanza internazionale
Articolo
Sì, ma tipo non specificato
Settore MED/25 - PSICHIATRIA
Settore MED/26 - NEUROLOGIA
English
Con Impact Factor ISI
Polymorphism, Single Nucleotide; Gene Frequency; Brain-Derived Neurotrophic Factor; Humans; Methionine; Schizophrenia; Adult; Schizophrenic Psychology; Middle Aged; Genetic Predisposition to Disease; Aggression; Female; Male; Valine
Spalletta, G., Morris, D., Angelucci, F., Rubino, I., Spoletini, I., Bria, P., et al. (2010). BDNF Val66Met polymorphism is associated with aggressive behavior in schizophrenia. EUROPEAN PSYCHIATRY, 25(6), 311-313.
Spalletta, G; Morris, D; Angelucci, F; Rubino, I; Spoletini, I; Bria, P; Martinotti, G; Siracusano, A; Bonaviri, G; Bernardini, S; Caltagirone, C; Bossù, P; Donohoe, G; Gill, M; Corvin, A
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/16209
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