Cortical and subcortical gray matter volumes were correlated with a set of linguistic scores in a group of schizophrenia patients. Lexical informativeness was positively associated with the volume of the left frontal cortical and accumbal areas, while left hippocampal atrophy and right ventricle enlargement predicted increased production of semantic paraphasias. Global coherence impairment was predicted by left accumbal volume reduction and left ventricle enlargement. These data confirm that the brain structure of specific cortical and subcortal areas, as determined by magnetic resonance imaging, is related to the compromised semantic retrieval and language control in schizophrenia.

Spalletta, G., Spoletini, I., Cherubini, A., Rubino, I., Siracusano, A., Piras, F., et al. (2010). Cortico-subcortical underpinnings of narrative processing impairment in schizophrenia. PSYCHIATRY RESEARCH, 182(1), 77-80 [10.1016/j.pscychresns.2009.11.001].

Cortico-subcortical underpinnings of narrative processing impairment in schizophrenia

RUBINO, IVO;SIRACUSANO, ALBERTO;CALTAGIRONE, CARLO;
2010-04-01

Abstract

Cortical and subcortical gray matter volumes were correlated with a set of linguistic scores in a group of schizophrenia patients. Lexical informativeness was positively associated with the volume of the left frontal cortical and accumbal areas, while left hippocampal atrophy and right ventricle enlargement predicted increased production of semantic paraphasias. Global coherence impairment was predicted by left accumbal volume reduction and left ventricle enlargement. These data confirm that the brain structure of specific cortical and subcortal areas, as determined by magnetic resonance imaging, is related to the compromised semantic retrieval and language control in schizophrenia.
apr-2010
Pubblicato
Rilevanza internazionale
Articolo
Sì, ma tipo non specificato
Settore MED/25 - PSICHIATRIA
Settore MED/26 - NEUROLOGIA
English
Con Impact Factor ISI
Schizophrenia; Magnetic Resonance Imaging; Cerebral Cortex; Humans; Schizophrenic Psychology; Language Disorders; Comprehension; Image Processing, Computer-Assisted; Cognition Disorders
Spalletta, G., Spoletini, I., Cherubini, A., Rubino, I., Siracusano, A., Piras, F., et al. (2010). Cortico-subcortical underpinnings of narrative processing impairment in schizophrenia. PSYCHIATRY RESEARCH, 182(1), 77-80 [10.1016/j.pscychresns.2009.11.001].
Spalletta, G; Spoletini, I; Cherubini, A; Rubino, I; Siracusano, A; Piras, F; Caltagirone, C; Marini, A
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/16208
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