The detection of PML-RAR by reverse transcription (RT) polymerase chain reaction (PCR) in acute promyelocytic leukemia (APL) patients who are in hematologic remission influences therapeutic decision making in several trials. In the light of this, the Spanish group has recently designed an external quality assessment program (EQAP) of RT-PCR detection of PML-RAR, which includes a study of sensitivity of the participating laboratories.
Bolufer, P., Lo Coco, F., Grimwade, D., Barragán, E., Diverio, D., Cassinat, B., et al. (2001). Variability in the levels of PML-RAR alpha fusion transcripts detected by the laboratories participating in an external quality control program using several reverse transcription polymerase chain reaction protocols. HAEMATOLOGICA, 86(6), 570-6.
Tipologia: | Articolo su rivista | |
Citazione: | Bolufer, P., Lo Coco, F., Grimwade, D., Barragán, E., Diverio, D., Cassinat, B., et al. (2001). Variability in the levels of PML-RAR alpha fusion transcripts detected by the laboratories participating in an external quality control program using several reverse transcription polymerase chain reaction protocols. HAEMATOLOGICA, 86(6), 570-6. | |
Lingua: | English | |
Settore Scientifico Disciplinare: | Settore MED/15 - Malattie del Sangue | |
Revisione (peer review): | Esperti anonimi | |
Tipo: | Articolo | |
Rilevanza: | Rilevanza internazionale | |
Stato di pubblicazione: | Pubblicato | |
Data di pubblicazione: | giu-2001 | |
Titolo: | Variability in the levels of PML-RAR alpha fusion transcripts detected by the laboratories participating in an external quality control program using several reverse transcription polymerase chain reaction protocols | |
Autori: | ||
Autori: | Bolufer, P; Lo Coco, F; Grimwade, D; Barragán, E; Diverio, D; Cassinat, B; Chomienne, C; Gonzalez, M; Colomer, D; Gomez, Mt; Marugan, I; Román, J; Delgado, Md; García-Marco, Ja; Bornstein, R; Vizmanos, Jl; Martinez, B; Jansen, J; Villegas, A; de Blas, Jm; Cabello, P; Sanz, Ma | |
Appare nelle tipologie: | 01 - Articolo su rivista |