Preliminary reports suggest that leukemic cell expression of CD56, a neural cell adhesion molecule, is associated with adverse clinical outcome in either acute myeloid leukemia with t(8;21) or acute promyelocytic leukemia (APL). We investigated the prognostic relevance of CD56 in a series of patients with APL who were treated homogeneously with all-trans-retinoic acid (ATRA) and chemotherapy.

Ferrara, F., Morabito, F., Martino, B., Specchia, G., Liso, V., Nobile, F., et al. (2000). CD56 expression is an indicator of poor clinical outcome in patients with acute promyelocytic leukemia treated with simultaneous all-trans-retinoic acid and chemotherapy. JOURNAL OF CLINICAL ONCOLOGY, 18(6), 1295-1300.

CD56 expression is an indicator of poor clinical outcome in patients with acute promyelocytic leukemia treated with simultaneous all-trans-retinoic acid and chemotherapy

LO COCO, FRANCESCO
2000-03-01

Abstract

Preliminary reports suggest that leukemic cell expression of CD56, a neural cell adhesion molecule, is associated with adverse clinical outcome in either acute myeloid leukemia with t(8;21) or acute promyelocytic leukemia (APL). We investigated the prognostic relevance of CD56 in a series of patients with APL who were treated homogeneously with all-trans-retinoic acid (ATRA) and chemotherapy.
mar-2000
Pubblicato
Rilevanza internazionale
Articolo
Esperti anonimi
Settore MED/15 - MALATTIE DEL SANGUE
English
Adolescent; Adult; Aged; Antigens, CD56; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Female; Humans; Idarubicin; Leukemia, Promyelocytic, Acute; Male; Middle Aged; Multivariate Analysis; Prognosis; Survival Analysis; Tretinoin
Ferrara, F., Morabito, F., Martino, B., Specchia, G., Liso, V., Nobile, F., et al. (2000). CD56 expression is an indicator of poor clinical outcome in patients with acute promyelocytic leukemia treated with simultaneous all-trans-retinoic acid and chemotherapy. JOURNAL OF CLINICAL ONCOLOGY, 18(6), 1295-1300.
Ferrara, F; Morabito, F; Martino, B; Specchia, G; Liso, V; Nobile, F; Boccuni, P; Di Noto, R; Pane, F; Annunziata, M; Schiavone, E; De Simone, M; Guglielmi, C; Del Vecchio, L; LO COCO, F
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/161819
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