Therapy-related acute promyelocytic leukemia (t-APL) has been increasingly reported after exposure to cytotoxic and/or immunosuppressive agents given for prior malignancies or autoimmune diseases. t-APL represents both a model for better understanding human leukemogenesis and an interesting therapeutic subset which requires specific adaptations for optimal management.

LO COCO, F., Hasan, S., Montesinos, P., Sanz, M. (2013). Biology and management of therapy-related acute promyelocytic leukemia. CURRENT OPINION IN ONCOLOGY, 25(6), 695-700 [10.1097/CCO.0000000000000013].

Biology and management of therapy-related acute promyelocytic leukemia

LO COCO, FRANCESCO;
2013-01-01

Abstract

Therapy-related acute promyelocytic leukemia (t-APL) has been increasingly reported after exposure to cytotoxic and/or immunosuppressive agents given for prior malignancies or autoimmune diseases. t-APL represents both a model for better understanding human leukemogenesis and an interesting therapeutic subset which requires specific adaptations for optimal management.
2013
Pubblicato
Rilevanza internazionale
Articolo
Esperti anonimi
Settore MED/15 - MALATTIE DEL SANGUE
English
Adult; Antineoplastic Agents; Arsenicals; Early Diagnosis; Female; Humans; Leukemia, Promyelocytic, Acute; Male; Middle Aged; Neoplasms, Second Primary; Oxides; Retrospective Studies; Risk Factors; Tretinoin
LO COCO, F., Hasan, S., Montesinos, P., Sanz, M. (2013). Biology and management of therapy-related acute promyelocytic leukemia. CURRENT OPINION IN ONCOLOGY, 25(6), 695-700 [10.1097/CCO.0000000000000013].
LO COCO, F; Hasan, S; Montesinos, P; Sanz, M
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/160513
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