In tuberous sclerosis complex (TSC) a relationship has been shown between early and refractory seizures and intellectual disability. However, it is uncertain whether epilepsy in TSC is simply a marker in infants who are destined to develop an encephalopathic process or if seizures play a causal role in developing an encephalopathy.

Curatolo, P., Aronica, E., Jansen, A., Jansen, F., Kotulska, K., Lagae, L., et al. (2016). Early onset epileptic encephalopathy or genetically determined encephalopathy with early onset epilepsy? Lessons learned from TSC. EUROPEAN JOURNAL OF PAEDIATRIC NEUROLOGY, 20(2), 203-211 [10.1016/j.ejpn.2015.12.005].

Early onset epileptic encephalopathy or genetically determined encephalopathy with early onset epilepsy? Lessons learned from TSC

CURATOLO, PAOLO;MOAVERO, ROMINA;
2016-03

Abstract

In tuberous sclerosis complex (TSC) a relationship has been shown between early and refractory seizures and intellectual disability. However, it is uncertain whether epilepsy in TSC is simply a marker in infants who are destined to develop an encephalopathic process or if seizures play a causal role in developing an encephalopathy.
Pubblicato
Rilevanza internazionale
Articolo
Esperti anonimi
Settore MED/39 - Neuropsichiatria Infantile
English
Epileptic encephalopathy; Genetics; Tuberous sclerosis; Vigabatrin; mTOR
Curatolo, P., Aronica, E., Jansen, A., Jansen, F., Kotulska, K., Lagae, L., et al. (2016). Early onset epileptic encephalopathy or genetically determined encephalopathy with early onset epilepsy? Lessons learned from TSC. EUROPEAN JOURNAL OF PAEDIATRIC NEUROLOGY, 20(2), 203-211 [10.1016/j.ejpn.2015.12.005].
Curatolo, P; Aronica, E; Jansen, A; Jansen, F; Kotulska, K; Lagae, L; Moavero, R; Jozwiak, S
Articolo su rivista
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2108/157527
Citazioni
  • ???jsp.display-item.citation.pmc??? 17
  • Scopus 44
  • ???jsp.display-item.citation.isi??? 38
social impact