Deep brain gray matter (GM) structures are involved in several neurodegenerative disorders and are affected by aging. In this study, we investigated the potential relationship between levels of brain-derived neurotrophic factor (BDNF), a putative biomarker of age- and clinically relevant brain dysfunctions, and the presence of structural modifications that were evaluated by magnetic resonance imaging in six deep GM structures.

Manna, A., Piras, F., Caltagirone, C., Bossu, P., Sensi, S., Spalletta, G. (2015). Left hippocampus-amygdala complex macro- and microstructural variation is associated with BDNF plasma levels in healthy elderly individuals. BRAIN AND BEHAVIOR, 5(7), e00334-n/a [10.1002/brb3.334].

Left hippocampus-amygdala complex macro- and microstructural variation is associated with BDNF plasma levels in healthy elderly individuals

CALTAGIRONE, CARLO;
2015-01-01

Abstract

Deep brain gray matter (GM) structures are involved in several neurodegenerative disorders and are affected by aging. In this study, we investigated the potential relationship between levels of brain-derived neurotrophic factor (BDNF), a putative biomarker of age- and clinically relevant brain dysfunctions, and the presence of structural modifications that were evaluated by magnetic resonance imaging in six deep GM structures.
2015
Pubblicato
Rilevanza internazionale
Articolo
Esperti anonimi
Settore MED/26 - NEUROLOGIA
English
BDNF; DTI; brain volume; Adolescent; Adult; Aged; Aging; Amygdala; Brain-Derived Neurotrophic Factor; Cohort Studies; Diffusion Tensor Imaging; Female; Functional Laterality; Hippocampus; Humans; Male; Middle Aged; Neuropsychological Tests; Regression Analysis; Young Adult
Manna, A., Piras, F., Caltagirone, C., Bossu, P., Sensi, S., Spalletta, G. (2015). Left hippocampus-amygdala complex macro- and microstructural variation is associated with BDNF plasma levels in healthy elderly individuals. BRAIN AND BEHAVIOR, 5(7), e00334-n/a [10.1002/brb3.334].
Manna, A; Piras, F; Caltagirone, C; Bossu, P; Sensi, S; Spalletta, G
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/155407
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