At least 14 iodinated proteins can be distinguished by SDS polyacrylamide gel electrophoresis followed by autoradiography in the membrane of intact human neutrophils. Neutrophils from patients suffering from rheumatoid arthritis show a modified expression of 4 outer membrane proteins. Three polypeptide components of the 30, 50 and 130 K were decreased by 95%, while the 120 K component dramatically increased. The possible relationship between the altered cell sensitivity and the defective expression of membrane proteins is discussed.
Spisani, S., Manservigi, R., Dovigo, L., Albonici Bove, L., & Traniello, S. (1985). Defective expression of neutrophil membrane proteins in patients with rheumatoid arthritis. JOURNAL OF CLINICAL & LABORATORY IMMUNOLOGY, 16(2), 77-9.
Tipologia: | Articolo su rivista |
Citazione: | Spisani, S., Manservigi, R., Dovigo, L., Albonici Bove, L., & Traniello, S. (1985). Defective expression of neutrophil membrane proteins in patients with rheumatoid arthritis. JOURNAL OF CLINICAL & LABORATORY IMMUNOLOGY, 16(2), 77-9. |
Lingua: | English |
Settore Scientifico Disciplinare: | Settore MED/46 - Scienze Tecniche di Medicina di Laboratorio |
Revisione (peer review): | Sì, ma tipo non specificato |
Tipo: | Articolo |
Rilevanza: | Rilevanza internazionale |
Stato di pubblicazione: | Pubblicato |
Data di pubblicazione: | feb-1985 |
Titolo: | Defective expression of neutrophil membrane proteins in patients with rheumatoid arthritis |
Autori: | |
Autori: | Spisani, S; Manservigi, R; Dovigo, L; Albonici Bove, L; Traniello, S |
Appare nelle tipologie: | 01 - Articolo su rivista |