At least 14 iodinated proteins can be distinguished by SDS polyacrylamide gel electrophoresis followed by autoradiography in the membrane of intact human neutrophils. Neutrophils from patients suffering from rheumatoid arthritis show a modified expression of 4 outer membrane proteins. Three polypeptide components of the 30, 50 and 130 K were decreased by 95%, while the 120 K component dramatically increased. The possible relationship between the altered cell sensitivity and the defective expression of membrane proteins is discussed.

Spisani, S., Manservigi, R., Dovigo, L., ALBONICI BOVE, L., Traniello, S. (1985). Defective expression of neutrophil membrane proteins in patients with rheumatoid arthritis. JOURNAL OF CLINICAL & LABORATORY IMMUNOLOGY, 16(2), 77-9.

Defective expression of neutrophil membrane proteins in patients with rheumatoid arthritis

ALBONICI BOVE, LOREDANA;
1985-02-01

Abstract

At least 14 iodinated proteins can be distinguished by SDS polyacrylamide gel electrophoresis followed by autoradiography in the membrane of intact human neutrophils. Neutrophils from patients suffering from rheumatoid arthritis show a modified expression of 4 outer membrane proteins. Three polypeptide components of the 30, 50 and 130 K were decreased by 95%, while the 120 K component dramatically increased. The possible relationship between the altered cell sensitivity and the defective expression of membrane proteins is discussed.
feb-1985
Pubblicato
Rilevanza internazionale
Articolo
Sì, ma tipo non specificato
Settore MED/46 - SCIENZE TECNICHE DI MEDICINA E DI LABORATORIO
English
Neutrophils; Middle Aged; Membrane Proteins; Aged; Adult; Arthritis, Rheumatoid; Humans; Cell Membrane
Spisani, S., Manservigi, R., Dovigo, L., ALBONICI BOVE, L., Traniello, S. (1985). Defective expression of neutrophil membrane proteins in patients with rheumatoid arthritis. JOURNAL OF CLINICAL & LABORATORY IMMUNOLOGY, 16(2), 77-9.
Spisani, S; Manservigi, R; Dovigo, L; ALBONICI BOVE, L; Traniello, S
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/14988
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