The effects of the Y2 receptor agonist neuropeptide Y NPY-(13-36) on the depolarization-evoked release of [3H]noradrenaline (NA) from synaptosomal preparations of the medulla oblongata, the hypothalamus, the hippocampal formation and the parieto-occipital cortex of the male rat were studied. NPY-(13-36) (0.1-100 nM) caused a concentration-related inhibition of the depolarization-induced release of [3H]NA in all areas studied, except the parieto-occipital cortex. The results indicate that NPY Y2 receptors are present on NA terminals in all areas studied, except the parieto-occipital cortex and inhibit depolarization-evoked [3H]NA release.
Martire, M., Pistritto, G., Mores, N., Agnati, L.F., & Fuxe, K. (1993). Region-specific inhibition of potassium-evoked [3H]noradrenaline release from rat brain synaptosomes by neuropeptide Y-(13-36). Involvement of NPY receptors of the Y2 type. EUROPEAN JOURNAL OF PHARMACOLOGY, 230(2), 231-234.
Tipologia: | Articolo su rivista |
Citazione: | Martire, M., Pistritto, G., Mores, N., Agnati, L.F., & Fuxe, K. (1993). Region-specific inhibition of potassium-evoked [3H]noradrenaline release from rat brain synaptosomes by neuropeptide Y-(13-36). Involvement of NPY receptors of the Y2 type. EUROPEAN JOURNAL OF PHARMACOLOGY, 230(2), 231-234. |
IF: | Con Impact Factor ISI |
Lingua: | English |
Settore Scientifico Disciplinare: | Settore BIO/14 |
Revisione (peer review): | Sì, ma tipo non specificato |
Tipo: | Articolo |
Rilevanza: | Rilevanza internazionale |
Stato di pubblicazione: | Pubblicato |
Data di pubblicazione: | 12-gen-1993 |
Titolo: | Region-specific inhibition of potassium-evoked [3H]noradrenaline release from rat brain synaptosomes by neuropeptide Y-(13-36). Involvement of NPY receptors of the Y2 type |
Autori: | |
Autori: | Martire, M; Pistritto, G; Mores, N; Agnati, LF; Fuxe, K |
Appare nelle tipologie: | 01 - Articolo su rivista |