Despite the emergence of several new effective treatments for metastatic castration-resistant prostate cancer patients, disease progression inevitably occurs, leading scientific community to carefully look for novel therapeutic targets of prostate cancer. Kallikrein (KLK)-related peptidases have been demonstrated to facilitate prostate tumorigenesis and disease progression through the development of an oncogenic microenvironment for prostate cells.

Cereda, V., Formica, V., Menghi, A., Pellicori, S., & Roselli, M. (2015). Kallikrein-related peptidases targeted therapies in prostate cancer: Perspectives and challenges. EXPERT OPINION ON INVESTIGATIONAL DRUGS, 24(7), 929-947 [10.1517/13543784.2015.1035708].

Kallikrein-related peptidases targeted therapies in prostate cancer: Perspectives and challenges

CEREDA, VITTORE;ROSELLI, MARIO
2015

Abstract

Despite the emergence of several new effective treatments for metastatic castration-resistant prostate cancer patients, disease progression inevitably occurs, leading scientific community to carefully look for novel therapeutic targets of prostate cancer. Kallikrein (KLK)-related peptidases have been demonstrated to facilitate prostate tumorigenesis and disease progression through the development of an oncogenic microenvironment for prostate cells.
Pubblicato
Rilevanza internazionale
Articolo
Esperti anonimi
Settore MED/06 - Oncologia Medica
English
engineered inhibitors; immunotherapy; kallikrein; kallikrein-activated prodrugs; kallikrein-targeted therapy; prostate cancer; Animals; Antineoplastic Agents; Humans; Kallikreins; Male; Prostatic Neoplasms
Cereda, V., Formica, V., Menghi, A., Pellicori, S., & Roselli, M. (2015). Kallikrein-related peptidases targeted therapies in prostate cancer: Perspectives and challenges. EXPERT OPINION ON INVESTIGATIONAL DRUGS, 24(7), 929-947 [10.1517/13543784.2015.1035708].
Cereda, V; Formica, V; Menghi, A; Pellicori, S; Roselli, M
Articolo su rivista
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2108/147628
Citazioni
  • ???jsp.display-item.citation.pmc??? 3
  • Scopus 5
  • ???jsp.display-item.citation.isi??? 6
social impact