Surgical cardiac revascularization produces a high degree of systemic inflammation and the secretion of several cytokines. Intensive postoperative inflammation may increase the incidence of postoperative atrial fibrillation and favor organ dysfunctions. No data documenting the anti-inflammatory properties of epicardial vagal ganglionated plexus stimulation are available.
Rossi, P., Ricci, A., DE PAULIS, R., Papi, E., Pavaci, H., Porcelli, D., et al. (2012). Epicardial ganglionated plexus stimulation decreases postoperative inflammatory response in humans. HEART RHYTHM, 9(6), 943-950 [10.1016/j.hrthm.2012.01.025].