Fluorine-substituted hydroxyapatites are considered promising materials for bone scaffolding. In this study a systematic investigation on F-half substituted hydroxyapatite (F-HAp, Ca10(PO4)6OHF) obtained by precipitation is reported. Results on composition analysis, thermal behaviour, and sinterability are presented for a comparison with the respective pure hydroxyapatite. Samples were characterised by electron microscopy, induced coupled plasma-atomic emission spectroscopy, thermal analysis, infrared spectroscopy, N2 adsorption measurements, X-ray diffraction and dilatometry. A semicrystalline F-substituted hydroxyapatite powder made up of needle-like nanoparticles was obtained. Notwithstanding that it was thermally stable up to 1300 8C, it was sintered at relatively low temperatures obtaining a very fine microstructure with a relevant nanoporosity, beneficial in view of cell adhesion and in-growth. Hardness, elastic modulus and toughness of produced samples were investigated by Vickers–Knoop microhardness testing. Significant improvements of the mechanical properties were observed for the F-substituted hydroxyapatite, in comparison with pure hydroxyapatite.

Bianco, A., Cacciotti, I., Lombardi, M., Montanaro, L., Bemporad, E., Sebastiani, M. (2010). F-substituted hydroxyapatite nanopowders: thermal stability, sintering behavior and mechanical properties,. CERAMICS INTERNATIONAL, 36, 313-322 [10.1016/j.ceramint.2009.09.007].

F-substituted hydroxyapatite nanopowders: thermal stability, sintering behavior and mechanical properties,

BIANCO, ALESSANDRA;
2010-01-01

Abstract

Fluorine-substituted hydroxyapatites are considered promising materials for bone scaffolding. In this study a systematic investigation on F-half substituted hydroxyapatite (F-HAp, Ca10(PO4)6OHF) obtained by precipitation is reported. Results on composition analysis, thermal behaviour, and sinterability are presented for a comparison with the respective pure hydroxyapatite. Samples were characterised by electron microscopy, induced coupled plasma-atomic emission spectroscopy, thermal analysis, infrared spectroscopy, N2 adsorption measurements, X-ray diffraction and dilatometry. A semicrystalline F-substituted hydroxyapatite powder made up of needle-like nanoparticles was obtained. Notwithstanding that it was thermally stable up to 1300 8C, it was sintered at relatively low temperatures obtaining a very fine microstructure with a relevant nanoporosity, beneficial in view of cell adhesion and in-growth. Hardness, elastic modulus and toughness of produced samples were investigated by Vickers–Knoop microhardness testing. Significant improvements of the mechanical properties were observed for the F-substituted hydroxyapatite, in comparison with pure hydroxyapatite.
2010
Pubblicato
Rilevanza internazionale
Articolo
Sì, ma tipo non specificato
Settore ING-IND/22 - SCIENZA E TECNOLOGIA DEI MATERIALI
English
Con Impact Factor ISI
SINTERING, APATITE, BIOMEDICAL APPLICATIONS, MECHANICAL PROPERTIES
http://www.sciencedirect.com/science/article/pii/S027288420900337X
Bianco, A., Cacciotti, I., Lombardi, M., Montanaro, L., Bemporad, E., Sebastiani, M. (2010). F-substituted hydroxyapatite nanopowders: thermal stability, sintering behavior and mechanical properties,. CERAMICS INTERNATIONAL, 36, 313-322 [10.1016/j.ceramint.2009.09.007].
Bianco, A; Cacciotti, I; Lombardi, M; Montanaro, L; Bemporad, E; Sebastiani, M
Articolo su rivista
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/13871
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