Transcatheter MitraClip repair is a new tool for the management of severe mitral regurgitation in patients at very high risk for conventional surgery. Aim of our study was reporting one-year clinical outcomes in candidates to MitraClip procedures, divided into three groups according to the cardiovascular medicine heart failure (CVM-HF) index. The study population consists of 46 consecutive patients, divided, in accordance with CVM-HF index, as follows: one patient in the low-risk category (group A); 27 patients in the medium-risk (group B) and 18 patients in high-risk category (group C). The primary study endpoint was a combined of all-cause mortality and re-hospitalization rate. Secondary endpoints were all-cause mortality and cardiac mortality. Patients of group B and group C were compared. Regarding the primary endpoint, patients in group C had significantly poorer outcomes than patients in group B, with a 12-month survival freedom from events of 44.4 and 74.1 %, respectively (log-rank test, p = 0.039); survival freedom from cardiac mortality was 100 and 83.3 % in group B and C, respectively (log-rank test, p = 0.027). One-year survival free from re-hospitalization was 74.1 % in group B and 39.9 % in group C (log-rank test; p = 0.036). Survival free from all-cause of mortality was 92.6 and 77.8 %, respectively (log-rank test; p = 0.129). In our initial experience the CVM-HF index showed to be valuable for understanding if the patient with advanced heart failure and functional mitral regurgitation can really benefit by MitraClip therapy.
USSIA, G.P., Cammalleri, V., Mazzotta, E., Pascuzzo, G., MUSCOLI, S., Marchei, M., et al. (2016). Cardiovascular medicine heart failure (CVM-HF) index as prognostic model for candidates to MitraClip therapy. HEART AND VESSELS, 31(10), 1633-1642.
|Tipologia:||Articolo su rivista|
|Citazione:||USSIA, G.P., Cammalleri, V., Mazzotta, E., Pascuzzo, G., MUSCOLI, S., Marchei, M., et al. (2016). Cardiovascular medicine heart failure (CVM-HF) index as prognostic model for candidates to MitraClip therapy. HEART AND VESSELS, 31(10), 1633-1642.|
|IF:||Con Impact Factor ISI|
|Settore Scientifico Disciplinare:||Settore MED/11 - Malattie dell'Apparato Cardiovascolare|
|Revisione (peer review):||Esperti anonimi|
|Digital Object Identifier (DOI):||http://dx.doi.org/10.1007/s00380-015-0772-z|
|Stato di pubblicazione:||Pubblicato|
|Data di pubblicazione:||2016|
|Titolo:||Cardiovascular medicine heart failure (CVM-HF) index as prognostic model for candidates to MitraClip therapy|
|Autori:||USSIA, GP; Cammalleri, V; Mazzotta, E; Pascuzzo, G; MUSCOLI, S; Marchei, M; Macrini, M; Anceschi, A; ROMEO, F|
|Appare nelle tipologie:||01 - Articolo su rivista|