FMRP, or fragile X mental retardation protein is an RNA-binding protein. Mutations in the FMRP protein have been associated with neurological disease as have a number of its mRNA-binding targets. This SnapShot presents 40 bona fide FMRP targets for which mRNA binding and protein regulation have been robustly reported in mammals along with the diseases with which they have been associated.
Pasciuto, E., Bagni, C. (2014). SnapShot: FMRP mRNA targets and diseases. CELL, 158(6), 1446e1 [10.1016/j.cell.2014.08.035].
SnapShot: FMRP mRNA targets and diseases
BAGNI, CLAUDIA
2014-09-11
Abstract
FMRP, or fragile X mental retardation protein is an RNA-binding protein. Mutations in the FMRP protein have been associated with neurological disease as have a number of its mRNA-binding targets. This SnapShot presents 40 bona fide FMRP targets for which mRNA binding and protein regulation have been robustly reported in mammals along with the diseases with which they have been associated.File in questo prodotto:
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