Mammary microcalcifications have a crucial role in breast cancer detection, but the processes that induce their formation are unknown. Moreover, recent studies have described the occurrence of the epithelial-mesenchymal transition (EMT) in breast cancer, but its role is not defined. In this study, we hypothesized that epithelial cells acquire mesenchymal characteristics and become capable of producing breast microcalcifications.
Scimeca, M., Giannini, E., Antonacci, C., Pistolese, C.a., Spagnoli, L.g., Bonanno, E. (2014). Microcalcifications in breast cancer: an active phenomenon mediated by epithelial cells with mesenchymal characteristics. BMC CANCER, 14, 286-286 [10.1186/1471-2407-14-286].
Microcalcifications in breast cancer: an active phenomenon mediated by epithelial cells with mesenchymal characteristics
Scimeca, M;PISTOLESE, CHIARA ADRIANA;SPAGNOLI, LUIGI GIUSTO;BONANNO, ELENA
2014-01-01
Abstract
Mammary microcalcifications have a crucial role in breast cancer detection, but the processes that induce their formation are unknown. Moreover, recent studies have described the occurrence of the epithelial-mesenchymal transition (EMT) in breast cancer, but its role is not defined. In this study, we hypothesized that epithelial cells acquire mesenchymal characteristics and become capable of producing breast microcalcifications.| File | Dimensione | Formato | |
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