Mammary microcalcifications have a crucial role in breast cancer detection, but the processes that induce their formation are unknown. Moreover, recent studies have described the occurrence of the epithelial-mesenchymal transition (EMT) in breast cancer, but its role is not defined. In this study, we hypothesized that epithelial cells acquire mesenchymal characteristics and become capable of producing breast microcalcifications.

Scimeca, M., Giannini, E., Antonacci, C., Pistolese, C.a., Spagnoli, L.g., & Bonanno, E. (2014). Microcalcifications in breast cancer: an active phenomenon mediated by epithelial cells with mesenchymal characteristics. BMC CANCER, 14, 286-286 [10.1186/1471-2407-14-286].

Microcalcifications in breast cancer: an active phenomenon mediated by epithelial cells with mesenchymal characteristics

Scimeca, M;PISTOLESE, CHIARA ADRIANA;SPAGNOLI, LUIGI GIUSTO;BONANNO, ELENA
2014

Abstract

Mammary microcalcifications have a crucial role in breast cancer detection, but the processes that induce their formation are unknown. Moreover, recent studies have described the occurrence of the epithelial-mesenchymal transition (EMT) in breast cancer, but its role is not defined. In this study, we hypothesized that epithelial cells acquire mesenchymal characteristics and become capable of producing breast microcalcifications.
Pubblicato
Rilevanza internazionale
Articolo
Esperti non anonimi
Settore MED/08 - Anatomia Patologica
eng
Con Impact Factor ISI
Scimeca, M., Giannini, E., Antonacci, C., Pistolese, C.a., Spagnoli, L.g., & Bonanno, E. (2014). Microcalcifications in breast cancer: an active phenomenon mediated by epithelial cells with mesenchymal characteristics. BMC CANCER, 14, 286-286 [10.1186/1471-2407-14-286].
Scimeca, M; Giannini, E; Antonacci, C; Pistolese, Ca; Spagnoli, Lg; Bonanno, E
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2108/133513
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