Gender-related differences in the pharmacological effects of drug are an emerging topic. This review examines gender differences in both pharmacokinetic and pharmacodynamic aspects of methadone, a long-acting opioid agonist that is prescribed as a treatment for opioid dependence and the management of chronic pain.
Graziani, M., Nistico', R.g. (2015). Gender differences in pharmacokinetics and pharmacodynamics of methadone substitution therapy. FRONTIERS IN PHARMACOLOGY, 6(5), 122 [10.3389/fphar.2015.00122].
Gender differences in pharmacokinetics and pharmacodynamics of methadone substitution therapy
NISTICO', ROBERT GIOVANNI
2015-01-01
Abstract
Gender-related differences in the pharmacological effects of drug are an emerging topic. This review examines gender differences in both pharmacokinetic and pharmacodynamic aspects of methadone, a long-acting opioid agonist that is prescribed as a treatment for opioid dependence and the management of chronic pain.File in questo prodotto:
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Descrizione: Gender differences in pharmacokinetics and pharmacodynamics of methadone substitution therapy
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