One-Electron Oxidation of Ferrocenes by Short-Lived N-oxyl Radicals. The Role of Structural Effects on the Intrinsic Electron Transfer Reactivities

A kinetic study of the one electron oxidation of substituted ferrocenes (FcX: X = H, COPh, COMe, CO2Et, CONH2, CH2OH, Et, and Me2) by a series of N-oxyl radicals (succinimide-N-oxyl radical (SINO), maleimide-N-oxyl radical (MINO), 3-quinazolin-4-one-N-oxyl radical (QONO) and 3-benzotriazin-4-one-N-oxyl radical (BONO)), has been carried out in CH3CN. N-oxyl radicals were produced by hydrogen abstraction from the corresponding N-hydroxy derivatives by the cumyloxyl radical. With all systems, the rate constants exhibited a satisfactory fit to the Marcus equation allowing us to determine self-exchange reorganization energy values (λNO˙/NO−) which have been compared with those previously determined for the PINO/PINO− and BTNO/BTNO− couples. Even small modification of the structure of the N-oxyl radicals lead to significant variation of the λNO˙/NO− values. The λNO˙/NO− values increase in the order BONO < BTNO < QONO < PINO < SINO < MINO which do not parallel the order of the oxidation potentials. The higher λNO˙/NO− values found for the MINO and SINO radicals might be in accordance with a lower degree of spin delocalization in the radicals MINO and SINO and charge delocalization in the anions MINO− and SINO− due to the absence of an aromatic ring in their structure.