Natural killer cells (NKs) are important effectors of the innate immune system, with marked antitumor activity. Imaging NK trafficking in vivo may be relevant to following up the efficacy of new therapeutic approaches aiming at increasing tumor-infiltrating NKs (TINKs). The specific aims of present study were to efficiently target NKs using a (99m)Tc-anti-CD56 and to image human NK trafficking in SCID mice bearing human cancer.

Galli, F., Rapisarda, A., Stabile, H., Malviya, G., Manni, I., Bonanno, E., et al. (2015). In Vivo Imaging of Natural Killer Cell Trafficking in Tumors. THE JOURNAL OF NUCLEAR MEDICINE, 56(10), 1575-1580 [10.2967/jnumed.114.152918].

In Vivo Imaging of Natural Killer Cell Trafficking in Tumors

BONANNO, ELENA;
2015-10-01

Abstract

Natural killer cells (NKs) are important effectors of the innate immune system, with marked antitumor activity. Imaging NK trafficking in vivo may be relevant to following up the efficacy of new therapeutic approaches aiming at increasing tumor-infiltrating NKs (TINKs). The specific aims of present study were to efficiently target NKs using a (99m)Tc-anti-CD56 and to image human NK trafficking in SCID mice bearing human cancer.
ott-2015
Pubblicato
Rilevanza internazionale
Articolo
Esperti anonimi
Settore MED/36 - DIAGNOSTICA PER IMMAGINI E RADIOTERAPIA
English
NK cells; TINKs; anti-CD56; imaging; nuclear medicine
Galli, F., Rapisarda, A., Stabile, H., Malviya, G., Manni, I., Bonanno, E., et al. (2015). In Vivo Imaging of Natural Killer Cell Trafficking in Tumors. THE JOURNAL OF NUCLEAR MEDICINE, 56(10), 1575-1580 [10.2967/jnumed.114.152918].
Galli, F; Rapisarda, A; Stabile, H; Malviya, G; Manni, I; Bonanno, E; Piaggio, G; Gismondi, A; Santoni, A; Signore, A
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/130674
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