The influence of neonatal beta-estradiol treatment on the development of GABA-degradative enzymes (GABA transaminase and succinic semialdehyde dehydrogenase) within rat cerebellar cortex has been studied using a semiquantitative histochemical technique. Both enzymatic activities were stimulated following beta-estradiol treatment. In particular, the granule and Purkinje cells were the most influenced cerebellar components. The findings seem to suggest that granule and Purkinje cells may represent the principal target of the cerebellar cortex for sex hormones.
Cavallotti, C., Iacopino, L., Amenta, F. (1983). Stimulatory effect of beta-estradiol treatment on GABA-degradative enzymes within rat cerebellar cortex. NEUROSCIENCE LETTERS, 39(2), 205-9.
Stimulatory effect of beta-estradiol treatment on GABA-degradative enzymes within rat cerebellar cortex
IACOPINO, LEONARDO;
1983-08-29
Abstract
The influence of neonatal beta-estradiol treatment on the development of GABA-degradative enzymes (GABA transaminase and succinic semialdehyde dehydrogenase) within rat cerebellar cortex has been studied using a semiquantitative histochemical technique. Both enzymatic activities were stimulated following beta-estradiol treatment. In particular, the granule and Purkinje cells were the most influenced cerebellar components. The findings seem to suggest that granule and Purkinje cells may represent the principal target of the cerebellar cortex for sex hormones.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.