Stimulatory effect of neonatal beta-estradiol treatment on aspartate-aminotransferase activity within rat cerebellar cortex

The effect of neonatal beta-estradiol treatment on the Aspartate-aminotransferase (Asp-T) activity within rat cerebellar cortex has been studied using a semi-quantitative histochemical technique. The Asp-T, localized chiefly at the level of nerve fiber-like structures in the molecular layer as well as around the perikaryon of Purkinje neurons, is significantly stimulated after estrogenization. The nerve fibers localized in the molecular layer were the Asp-T cerebellar structures more remarkably influenced by beta-estradiol treatment.