Human immunodeficiency virus (HIV) chronically infected patients are at increased risk of developing non-Hodgkin lymphoma compared with the general population. Highly active antiretroviral therapy has had a dramatic effect on the natural history of HIV infection, reducing the incidence of acquired immunodeficiency syndrome-related non-Hodgkin lymphoma and improving overall survival. However, problems related to adherence to treatment, frequently experienced during adolescence, may increase the risk of acquired immunodeficiency syndrome-related cancers. Optimizing highly active antiretroviral therapy and monitoring noncompliant patients with persisting HIV replication should be considered by physicians who take care of these patients. We herein report 2 cases of relapsed/progressive Burkitt lymphoma in HIV vertically infected adolescents.

Zangari, P., Santilli, V., Cotugno, N., Manno, E., Palumbo, G., Lombardi, A., et al. (2013). Raising awareness of non-hodgkin lymphoma in HIV-infected adolescents: Report of 2 cases in the HAART era. JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY, 35(3), e134-e137 [10.1097/MPH.0b013e318282cef5].

Raising awareness of non-hodgkin lymphoma in HIV-infected adolescents: Report of 2 cases in the HAART era

Cotugno, N;PALUMBO, GIUSEPPE;Palma, P;
2013

Abstract

Human immunodeficiency virus (HIV) chronically infected patients are at increased risk of developing non-Hodgkin lymphoma compared with the general population. Highly active antiretroviral therapy has had a dramatic effect on the natural history of HIV infection, reducing the incidence of acquired immunodeficiency syndrome-related non-Hodgkin lymphoma and improving overall survival. However, problems related to adherence to treatment, frequently experienced during adolescence, may increase the risk of acquired immunodeficiency syndrome-related cancers. Optimizing highly active antiretroviral therapy and monitoring noncompliant patients with persisting HIV replication should be considered by physicians who take care of these patients. We herein report 2 cases of relapsed/progressive Burkitt lymphoma in HIV vertically infected adolescents.
Pubblicato
Rilevanza internazionale
Articolo
Esperti anonimi
Settore MED/38 - Pediatria Generale e Specialistica
English
Adolescent; Antineoplastic Combined Chemotherapy Protocols; Awareness; HIV Infections; HIV-1; Humans; Lymphoma, AIDS-Related; Lymphoma, Non-Hodgkin; Male; Antiretroviral Therapy, Highly Active
Zangari, P., Santilli, V., Cotugno, N., Manno, E., Palumbo, G., Lombardi, A., et al. (2013). Raising awareness of non-hodgkin lymphoma in HIV-infected adolescents: Report of 2 cases in the HAART era. JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY, 35(3), e134-e137 [10.1097/MPH.0b013e318282cef5].
Zangari, P; Santilli, V; Cotugno, N; Manno, E; Palumbo, G; Lombardi, A; De Vito, R; Tchidjou, H; Baldassari, S; Ariganello, P; Pontrelli, G; De Florio, F; Palma, P; Bernardi, S
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2108/129966
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