INTRODUCTION: The lack of consistent official information on the use of medications during lactation is probably one of the main reasons leading to an excess of prudence, based on presumption of risk rather than on evidence. The objective of this study was to compare the level of agreement between different official sources available to doctors and women on the use of medications during lactation. MATERIALS AND METHODS: Sources of information included governmental regulatory agencies (RAs) and scientific sources (SS). The package leaflets (PLs) and summaries of product characteristics (SPCs) were retrieved from online databases of the European Union and U.S. RAs. Among the SS, the latest edition of the book Medications and Mothers' Milk by Hale and Rowe and the LactMed database were selected. Information about the use of 11 antihypertensive medications during breastfeeding was analyzed. RESULTS: The PLs and SPCs report a higher risk profile than the one expressed by SS, and they often suggest the interruption of lactation even for compatible medications. CONCLUSIONS: Health professionals should be supported by official, accurate, comprehensive, and consistent information about maternally ingested medication and breastfeeding management to facilitate proper decision-making

Colaceci, S., Giusti, A., Chapin, E., Notarangelo, M., De Angelis, A., Vellone, E., et al. (2015). The Difficulties in Antihypertensive Drug Prescription During Lactation: Is the Information Consistent?. BREASTFEEDING MEDICINE, 10(10), 468-473 [10.1089/bfm.2015.0086].

The Difficulties in Antihypertensive Drug Prescription During Lactation: Is the Information Consistent?

VELLONE, ERCOLE;ALVARO, ROSARIA
2015-11-13

Abstract

INTRODUCTION: The lack of consistent official information on the use of medications during lactation is probably one of the main reasons leading to an excess of prudence, based on presumption of risk rather than on evidence. The objective of this study was to compare the level of agreement between different official sources available to doctors and women on the use of medications during lactation. MATERIALS AND METHODS: Sources of information included governmental regulatory agencies (RAs) and scientific sources (SS). The package leaflets (PLs) and summaries of product characteristics (SPCs) were retrieved from online databases of the European Union and U.S. RAs. Among the SS, the latest edition of the book Medications and Mothers' Milk by Hale and Rowe and the LactMed database were selected. Information about the use of 11 antihypertensive medications during breastfeeding was analyzed. RESULTS: The PLs and SPCs report a higher risk profile than the one expressed by SS, and they often suggest the interruption of lactation even for compatible medications. CONCLUSIONS: Health professionals should be supported by official, accurate, comprehensive, and consistent information about maternally ingested medication and breastfeeding management to facilitate proper decision-making
Pubblicato
Rilevanza internazionale
Articolo
Esperti anonimi
Settore MED/45 - Scienze Infermieristiche Generali, Cliniche e Pediatriche
Settore MED/47 - Scienze Infermieristiche Ostetrico-Ginecologiche
English
Con Impact Factor ISI
Colaceci, S., Giusti, A., Chapin, E., Notarangelo, M., De Angelis, A., Vellone, E., et al. (2015). The Difficulties in Antihypertensive Drug Prescription During Lactation: Is the Information Consistent?. BREASTFEEDING MEDICINE, 10(10), 468-473 [10.1089/bfm.2015.0086].
Colaceci, S; Giusti, A; Chapin, E; Notarangelo, M; De Angelis, A; Vellone, E; Alvaro, R
Articolo su rivista
File in questo prodotto:
File Dimensione Formato  
Colaceci_2015_Antihypertensive drug during lactation_In Press.pdf

accesso solo dalla rete interna

Licenza: Copyright dell'editore
Dimensione 3.2 MB
Formato Adobe PDF
3.2 MB Adobe PDF   Visualizza/Apri   Richiedi una copia

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/126772
Citazioni
  • ???jsp.display-item.citation.pmc??? 3
  • Scopus 15
  • ???jsp.display-item.citation.isi??? 12
social impact