Background: Depression goes often unrecognised and untreated in non-psychiatric medical settings. Screening has recently gained acceptance as a first step towards improving depression recognition and management. The Primary Care Screener for Affective Disorders (PC-SAD) is a self-administered questionnaire to screen for Major Depressive Disorder (MDD) and Dysthymic Disorder (Dys) which has a sophisticated scoring algorithm that confers several advantages. This study tested its performance against a ‘gold standard’ diagnostic interview in primary care. Methods: A total of 416 adults attending 13 urban general internal medicine primary care practices completed the PC-SAD. Of 409 who returned a valid PC-SAD, all those scoring positive (N=151) and a random sample (N=106) of those scoring negative were selected for a 3-month telephone follow-up assessment including the administration of the Structured Clinical Interview for DSM-IV-TR Axis I Disorders (SCID-I) by a psychiatrist who was masked to PC-SAD results. Results: Most selected patients (N=212) took part in the follow-up assessment. After adjustment for partial verification bias the sensitivity, specificity, positive and negative predictive value for MDD were 90%, 83%, 51%, and 98%. For Dys, the corresponding figures were 78%, 79%, 8%, and 88%. Conclusions: While some study limitations suggest caution in interpreting our results, this study corroborated the diagnostic validity of the PC-SAD, although the low PPV may limit its usefulness with regard to Dys. Given its good psychometric properties and the short average administration time, the PC-SAD might be the screening instrument of choice in settings where the technology for computer automated scoring is available.
|Tipologia:||Articolo su rivista|
|Citazione:||Picardi, A., Adler, D., Rogers, W., Lega, I., Zerella, M., Matteucci, G., et al. (2013). Diagnostic accuracy of the primary care screener for affective disorder (PC-SAD) in primary care. CLINICAL PRACTICE AND EPIDEMIOLOGY IN MENTAL HEALTH, 164-170.|
|Settore Scientifico Disciplinare:||Settore SECS-P/06 - Economia Applicata|
|Revisione (peer review):||Sì, ma tipo non specificato|
|Digital Object Identifier (DOI):||10.2174/1745017901309010164|
|Stato di pubblicazione:||Pubblicato|
|Data di pubblicazione:||2013|
|Titolo:||Diagnostic accuracy of the primary care screener for affective disorder (PC-SAD) in primary care|
|Autori interni:||SPANDONARO, FEDERICO|
|Autori:||Picardi, A; Adler, D.A; Rogers, W.H; Lega, I; Zerella, M.P; Matteucci, G; Tarsitani, L; Caredda, M; Gigantesco, A; Biondi, M; Cerbo, M; Gaddini, A; Gigantesco, A; Spandonaro, F; Cavallo, A; Crescenzi, A; Polistena, B; Berardelli, I; Cascavilla, I; Re, D; Fini, C; Leoncini, L; Baccarini, S; D'Andrea, F; Fonso, M.D; Dolfi, R; Guerani, A; Mandolini, D; Marri, G; Pagano, L; Pagliarini, M; Paoletti, M.L; Pes, A; Raspa, S; Sabatini, M; Salomone, U; Ventura, P|
|Appare nelle tipologie:||01 - Articolo su rivista|
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