There is evidence that platelets may be used locally as a source of growth factors that play a fundamental role in wound healing. From October 2008 to September 2009, at Tor Vergata Rome University Hospital, seven patients were enrolled in the study. All of these patients had ulcers with a extension over 3.5 cm(2). Four patients achieved a total recovery of the ulcers, while three experienced a reduction of the diameter of the ulcers. Our data are preliminary, but it is possible to suggest that recovery of the ulcers using the FIBRINET® system is related to platelet activation in the specific ulcer area.

Marinacci, M., Del Proposto, G., Catapano, A., Ferraro, A., Cerrone, P., Lanti, A., et al. (2010). Treatment of diabetic ulcers, using autologous platelet and fibrinic gel. Experience the FIBRINET® device. TRANSFUSION AND APHERESIS SCIENCE, 43(2), 171-172 [10.1016/j.transci.2010.07.013].

Treatment of diabetic ulcers, using autologous platelet and fibrinic gel. Experience the FIBRINET® device

UCCIOLI, LUIGI;ADORNO, GASPARE;ISACCHI, GIANCARLO
2010-10-01

Abstract

There is evidence that platelets may be used locally as a source of growth factors that play a fundamental role in wound healing. From October 2008 to September 2009, at Tor Vergata Rome University Hospital, seven patients were enrolled in the study. All of these patients had ulcers with a extension over 3.5 cm(2). Four patients achieved a total recovery of the ulcers, while three experienced a reduction of the diameter of the ulcers. Our data are preliminary, but it is possible to suggest that recovery of the ulcers using the FIBRINET® system is related to platelet activation in the specific ulcer area.
ott-2010
Pubblicato
Rilevanza internazionale
Articolo
Sì, ma tipo non specificato
Settore MED/09 - MEDICINA INTERNA
Settore MED/05 - PATOLOGIA CLINICA
English
Con Impact Factor ISI
Male; Blood Platelets; Middle Aged; Female; Diabetic Foot; Equipment Design; Fibrin; Humans; Flow Cytometry; Wound Healing; Equipment and Supplies; Platelet Activation; Blood Pressure; Aged
Marinacci, M., Del Proposto, G., Catapano, A., Ferraro, A., Cerrone, P., Lanti, A., et al. (2010). Treatment of diabetic ulcers, using autologous platelet and fibrinic gel. Experience the FIBRINET® device. TRANSFUSION AND APHERESIS SCIENCE, 43(2), 171-172 [10.1016/j.transci.2010.07.013].
Marinacci, M; Del Proposto, G; Catapano, A; Ferraro, A; Cerrone, P; Lanti, A; Uccioli, L; Giurato, L; D'Ambrogi, E; Adorno, G; Isacchi, G
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/12546
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