In an open, randomized clinical study, the safety and efficacy of sulbactam/ampicillin was compared to that of cefotetan in 95 hospital patients with gynecologic or obstetric infections. Sulbactam/ampicillin (1 g:2 g), was administered intravenously every 8 h to 46 patients, and cefotetan (2 g) was administered intravenously every 12 h to 49 patients. All 23 patients with obstetric infections and 18 of the 23 patients with gynecologic infections treated with sulbactam/ampicillin were evaluated as cured. All 21 patients with obstetric infections and 23 of the 28 patients with gynecologic infections treated with cefotetan were evaluated as cured. No side effects requiring discontinuation of therapy or reduction of the dose administered, were observed.

Scalambrino, S., Mangioni, C., Milani, R., Regallo, M., Norchi, S., Negri, L., et al. (1989). Sulbactam/ampicillin versus cefotetan in the treatment of obstetric and gynecologic infections. SUPPLEMENT TO INTERNATIONAL JOURNAL OF GYNECOLOGY AND OBSTETRICS, 2, 21-27.

Sulbactam/ampicillin versus cefotetan in the treatment of obstetric and gynecologic infections

CANALE, MARIA PAOLA
1989-01-01

Abstract

In an open, randomized clinical study, the safety and efficacy of sulbactam/ampicillin was compared to that of cefotetan in 95 hospital patients with gynecologic or obstetric infections. Sulbactam/ampicillin (1 g:2 g), was administered intravenously every 8 h to 46 patients, and cefotetan (2 g) was administered intravenously every 12 h to 49 patients. All 23 patients with obstetric infections and 18 of the 23 patients with gynecologic infections treated with sulbactam/ampicillin were evaluated as cured. All 21 patients with obstetric infections and 23 of the 28 patients with gynecologic infections treated with cefotetan were evaluated as cured. No side effects requiring discontinuation of therapy or reduction of the dose administered, were observed.
Pubblicato
Rilevanza internazionale
Articolo
Esperti anonimi
Settore MED/09 - Medicina Interna
English
Adult; Aged; Ampicillin; Bacterial Infections; Cefotetan; Drug Therapy, Combination; Female; Genital Diseases, Female; Humans; Middle Aged; Pregnancy; Pregnancy Complications, Infectious; Randomized Controlled Trials as Topic; Sulbactam
Scalambrino, S., Mangioni, C., Milani, R., Regallo, M., Norchi, S., Negri, L., et al. (1989). Sulbactam/ampicillin versus cefotetan in the treatment of obstetric and gynecologic infections. SUPPLEMENT TO INTERNATIONAL JOURNAL OF GYNECOLOGY AND OBSTETRICS, 2, 21-27.
Scalambrino, S; Mangioni, C; Milani, R; Regallo, M; Norchi, S; Negri, L; Carrera, S; Vigano, E; Ruffilli, M; Canale, Mp
Articolo su rivista
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/121978
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