Therapeutic angiogenesis by autologous-peripheral blood mononuclear cells (A-PBMNC) implantation has been shown to be a safe and effective treatment for critical limb ischemia (CLI). We herein report our investigation of the long-term efficacy of implantation of A-PBMNC produced by selective filtration to treat patients with CLI, for which surgical bypass and/or percutaneous transluminal angioplasty are not possible.
De Angelis, B., Gentile, P., Orlandi, F., Bocchini, I., Di Pasquali, C., Agovino, A., et al. (2015). Limb rescue: a new autologous-peripheral blood mononuclear cells technology in critical limb ischemia and chronic ulcers. TISSUE ENGINEERING. PART C METHODS, 21(5), 423-435 [10.1089/ten.TEC.2014.0245].
Limb rescue: a new autologous-peripheral blood mononuclear cells technology in critical limb ischemia and chronic ulcers
De Angelis, B;Gentile, P;SCIOLI, MARIA GIOVANNA;ORLANDI, AUGUSTO;CERVELLI, VALERIO
2015-05-01
Abstract
Therapeutic angiogenesis by autologous-peripheral blood mononuclear cells (A-PBMNC) implantation has been shown to be a safe and effective treatment for critical limb ischemia (CLI). We herein report our investigation of the long-term efficacy of implantation of A-PBMNC produced by selective filtration to treat patients with CLI, for which surgical bypass and/or percutaneous transluminal angioplasty are not possible.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.