Mesenchymal stromal cells (MSCs) are considered an important therapeutic tool in cancer therapy. They possess intrinsic therapeutic potential and can also be in vitro manipulated and engineered to produce therapeutic molecules that can be delivered to the site of diseases, through their capacity to home pathological tissues. We have recently demonstrated that MSCs, upon in vitro priming with anti-cancer drug, become drug-releasing mesenchymal cells (Dr-MCs) able to strongly inhibit cancer cells growth.

Pessina, A., Leonetti, C., Artuso, S., Benetti, A., Dessy, E., Pascucci, L., et al. (2015). Drug-releasing mesenchymal cells strongly suppress B16 lung metastasis in a syngeneic murine model. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, 34(1), 82 [10.1186/s13046-015-0200-3].

Drug-releasing mesenchymal cells strongly suppress B16 lung metastasis in a syngeneic murine model

ORLANDI, AUGUSTO;
2015-08-01

Abstract

Mesenchymal stromal cells (MSCs) are considered an important therapeutic tool in cancer therapy. They possess intrinsic therapeutic potential and can also be in vitro manipulated and engineered to produce therapeutic molecules that can be delivered to the site of diseases, through their capacity to home pathological tissues. We have recently demonstrated that MSCs, upon in vitro priming with anti-cancer drug, become drug-releasing mesenchymal cells (Dr-MCs) able to strongly inhibit cancer cells growth.
ago-2015
Pubblicato
Rilevanza internazionale
Articolo
Esperti anonimi
Settore MED/06 - ONCOLOGIA MEDICA
English
Con Impact Factor ISI
Pessina, A., Leonetti, C., Artuso, S., Benetti, A., Dessy, E., Pascucci, L., et al. (2015). Drug-releasing mesenchymal cells strongly suppress B16 lung metastasis in a syngeneic murine model. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, 34(1), 82 [10.1186/s13046-015-0200-3].
Pessina, A; Leonetti, C; Artuso, S; Benetti, A; Dessy, E; Pascucci, L; Passeri, D; Orlandi, A; Berenzi, A; Bonomi, A; Cocce, V; Ceserani, V; Ferri, A;...espandi
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/119917
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