Vitamin C is an essential dietary nutrient for the biosynthesis of collagen and a co-factor in the biosynthesis of catecholamines, L-carnitine, cholesterol, amino acids, and some peptide hormones. The lack of vitamin C causes scurvy, a pathological condition leading to blood vessel fragility and connective tissue damage due to failure in producing collagen, and, finally, to death as result of a general collapse. Vitamin C is potentially involved also in cancer and cardiovascular diseases prevention. In addition, vitamin C effects on nervous system and chronically ill patients have been also documented. This review attempts to summarize recent and well established advances in vitamin C research and its clinical implications. Since vitamin C has the potential to counteract inflammation and subsequent oxidative damage that play a major role in the initiation and progression of several chronic and acute diseases, it represents a practical tool to administer for the early prevention of these pathologic conditions.

Grosso, G., Bei, R., Mistretta, A., Marventano, S., Calabrese, G., Masuelli, L., et al. (2013). Effects of Vitamin C on health: a review of evidence. FRONTIERS IN BIOSCIENCE, 18(3), 1017-1029 [10.2741/4160].

Effects of Vitamin C on health: a review of evidence

BEI, ROBERTO;GIGANTI, MARIA GABRIELLA;MODESTI, ANDREA;
2013-06-01

Abstract

Vitamin C is an essential dietary nutrient for the biosynthesis of collagen and a co-factor in the biosynthesis of catecholamines, L-carnitine, cholesterol, amino acids, and some peptide hormones. The lack of vitamin C causes scurvy, a pathological condition leading to blood vessel fragility and connective tissue damage due to failure in producing collagen, and, finally, to death as result of a general collapse. Vitamin C is potentially involved also in cancer and cardiovascular diseases prevention. In addition, vitamin C effects on nervous system and chronically ill patients have been also documented. This review attempts to summarize recent and well established advances in vitamin C research and its clinical implications. Since vitamin C has the potential to counteract inflammation and subsequent oxidative damage that play a major role in the initiation and progression of several chronic and acute diseases, it represents a practical tool to administer for the early prevention of these pathologic conditions.
Pubblicato
Rilevanza internazionale
Articolo
Esperti anonimi
Settore MED/04 - Patologia Generale
English, Middle (1100-1500)
Con Impact Factor ISI
Author Keywords:Vitamin C; Ascorbic Acid; Cardiovascular Disease; Cancer; Anti-Inflammation; Antioxidant; Review KeyWords Plus:LOW-DENSITY-LIPOPROTEIN; OXIDATIVE DNA-DAMAGE; SMOOTH-MUSCLE-CELLS; NITRIC-OXIDE SYNTHASE; NICOTINAMIDE ADENINE-DINUCLEOTIDE; VASCULAR ENDOTHELIAL-CELLS; CORONARY-ARTERY-DISEASE; CRITICALLY-ILL PATIENTS; ASCORBIC-ACID PROTECTS; GAMMA-LACTONE OXIDASE
Grosso, G., Bei, R., Mistretta, A., Marventano, S., Calabrese, G., Masuelli, L., et al. (2013). Effects of Vitamin C on health: a review of evidence. FRONTIERS IN BIOSCIENCE, 18(3), 1017-1029 [10.2741/4160].
Grosso, G; Bei, R; Mistretta, A; Marventano, S; Calabrese, G; Masuelli, L; Giganti, Mg; Modesti, A; Galvano, F; Gazzolo, D
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/119766
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