Distal and lateral onychomycoses are the most frequent forms of onychomycosis, causing subungual hyperkeratosis that usually limits local penetration of antimycotic drugs. Tazarotene exerts anti-inflammatory and immune-modulating activities toward both infective agents and damaged keratinocytes. Given the well-documented efficacy of tazarotene on hyperkeratotic nail psoriasis, we investigated its therapeutic use in onychomycosis.
Campione, E., Paterno, E., Costanza, G., Diluvio, L., Carboni, I., Marino, D., et al. (2015). Tazarotene as alternative topical treatment for onychomycosis. DRUG DESIGN, DEVELOPMENT AND THERAPY, 9, 879-886 [10.2147/DDDT.S69946].
Tazarotene as alternative topical treatment for onychomycosis
Campione, E;CARBONI, ISABELLA;FAVALLI, CARTESIO;CHIMENTI, SERGIO;BIANCHI, LUCA;ORLANDI, AUGUSTO
2015-01-01
Abstract
Distal and lateral onychomycoses are the most frequent forms of onychomycosis, causing subungual hyperkeratosis that usually limits local penetration of antimycotic drugs. Tazarotene exerts anti-inflammatory and immune-modulating activities toward both infective agents and damaged keratinocytes. Given the well-documented efficacy of tazarotene on hyperkeratotic nail psoriasis, we investigated its therapeutic use in onychomycosis.| File | Dimensione | Formato | |
|---|---|---|---|
|
tazarotene-as-alternative-treatment-for-onychomycosis.pdf
solo utenti autorizzati
Descrizione: Articolo principale
Licenza:
Copyright dell'editore
Dimensione
6.94 MB
Formato
Adobe PDF
|
6.94 MB | Adobe PDF | Visualizza/Apri Richiedi una copia |
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
