We describe the use of a polymerase chain reaction in conjunction with a DNA enzyme immunoassay for the simultaneous detection of five common cystic fibrosis mutations. The method is specific, sensitive, rapid, and proved effective in Guthrie card-based screening of cystic fibrosis mutations.
Sangiuolo, F.c., Maceratesi, P., Mesoraca, A., Botta, A., Cavicchini, A., Novelli, G., et al. (1995). Simultaneous detection of delta F508, G542X, N1303K, G551D, and 1717-1G-->A cystic fibrosis alleles by a multiplex DNA enzyme immunoassay. INTERNATIONAL JOURNAL OF CLINICAL & LABORATORY RESEARCH, 25(3), 142-145 [10.1007/BF02592555].
Simultaneous detection of delta F508, G542X, N1303K, G551D, and 1717-1G-->A cystic fibrosis alleles by a multiplex DNA enzyme immunoassay
SANGIUOLO, FEDERICA CARLA;BOTTA, ANNALISA;NOVELLI, GIUSEPPE;
1995-01-01
Abstract
We describe the use of a polymerase chain reaction in conjunction with a DNA enzyme immunoassay for the simultaneous detection of five common cystic fibrosis mutations. The method is specific, sensitive, rapid, and proved effective in Guthrie card-based screening of cystic fibrosis mutations.File in questo prodotto:
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