The interplay between genetic susceptibility and exposure to carcinogens has been shown to be involved in the etiology of many solid tumors. We studied the frequency and clinical correlates of polymorphisms resulting in deletions of two genes involved in the detoxification of potentially carcinogenic agents, glutathione S-transferase (GST)-M1 and GSTT1 in patients with Hodgkin's lymphoma (HL).

Hohaus, S., Massini, G., D'Alo', F., Guidi, F., Putzulu, R., Scardocci, A., et al. (2003). Association between glutathione S-transferase genotypes and Hodgkin's lymphoma risk and prognosis. CLINICAL CANCER RESEARCH, 9(9), 3435-3440.

Association between glutathione S-transferase genotypes and Hodgkin's lymphoma risk and prognosis

VOSO, MARIA TERESA;
2003-08-15

Abstract

The interplay between genetic susceptibility and exposure to carcinogens has been shown to be involved in the etiology of many solid tumors. We studied the frequency and clinical correlates of polymorphisms resulting in deletions of two genes involved in the detoxification of potentially carcinogenic agents, glutathione S-transferase (GST)-M1 and GSTT1 in patients with Hodgkin's lymphoma (HL).
15-ago-2003
Pubblicato
Rilevanza internazionale
Articolo
Esperti anonimi
Settore MED/15 - MALATTIE DEL SANGUE
English
Adolescent; Adult; Aged; Cell Differentiation; Disease-Free Survival; Female; Gene Deletion; Genes, bcl-2; Genotype; Glutathione Transferase; Hodgkin Disease; Humans; Male; Middle Aged; Odds Ratio; Polymerase Chain Reaction; Polymorphism, Genetic; Prognosis; Risk; Time Factors
Hohaus, S., Massini, G., D'Alo', F., Guidi, F., Putzulu, R., Scardocci, A., et al. (2003). Association between glutathione S-transferase genotypes and Hodgkin's lymphoma risk and prognosis. CLINICAL CANCER RESEARCH, 9(9), 3435-3440.
Hohaus, S; Massini, G; D'Alo', F; Guidi, F; Putzulu, R; Scardocci, A; Rabi, A; Di Febo, A; Voso, Mt; Leone, G
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/117016
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