In previous phase 1-2 clinical trials involving older adults, a subunit vaccine containing varicella-zoster virus glycoprotein E and the AS01B adjuvant system (called HZ/su) had a clinically acceptable safety profile and elicited a robust immune response.

Lal, H., Cunningham, A., Godeaux, O., Chlibek, R., Diez Domingo, J., Hwang, S., et al. (2015). Efficacy of an adjuvanted herpes zoster subunit vaccine in older adults. THE NEW ENGLAND JOURNAL OF MEDICINE, 372(22), 2087-2096 [10.1056/NEJMoa1501184].

Efficacy of an adjuvanted herpes zoster subunit vaccine in older adults

VOLPI, ANTONIO;
2015-05-01

Abstract

In previous phase 1-2 clinical trials involving older adults, a subunit vaccine containing varicella-zoster virus glycoprotein E and the AS01B adjuvant system (called HZ/su) had a clinically acceptable safety profile and elicited a robust immune response.
mag-2015
Pubblicato
Rilevanza internazionale
Articolo
Esperti anonimi
Settore MED/17 - MALATTIE INFETTIVE
English
Adjuvants, Immunologic; Aged; Double-Blind Method; Female; Herpes Zoster; Herpes Zoster Vaccine; Humans; Injections, Intramuscular; Male; Middle Aged; Treatment Outcome; Vaccines, Subunit
Lal, H., Cunningham, A., Godeaux, O., Chlibek, R., Diez Domingo, J., Hwang, S., et al. (2015). Efficacy of an adjuvanted herpes zoster subunit vaccine in older adults. THE NEW ENGLAND JOURNAL OF MEDICINE, 372(22), 2087-2096 [10.1056/NEJMoa1501184].
Lal, H; Cunningham, A; Godeaux, O; Chlibek, R; Diez Domingo, J; Hwang, S; Levin, M; Mcelhaney, J; Poder, A; Puig, B; J, ; Vesikari, T; Watanabe, D; Weckx, L; Zahaf, T; Heineman, T; Arya, M; Athan, E; Cunningham, A; De Looze, F; Seale, J; Yeo, W; Goldani, L; Jacob, W; Luiz Neto, J; dos Santos, R; Weckx, L; Zerbini, C; Dutz, J; Ghesquiere, W; Gorfinkel, I; Mcelhaney, J; Mcneil, S; Powell, C; Chlibek, R; Smetana, J; Poder, A; Ahonen, A; Korhonen, T; Seppa, I; Vesikari, T; Arnou, R; Beytout, J; Saillard, D; Dominicus, R; Esen, M; Plaßmann, G; Schwarz, T; Tyler, K; Hui, D; Leung, E; Pellegrino, A; Volpi, A; Endo, M; Watanabe, D; Cheong, H; Choi, W; Choo, E; Kim, Y; Lee, J; Park, D; Peck, K; Song, Y; Barba Gómez, J; de Los Santos, A; Tinoco, J; Bayas, J; Caso, C; Roure, J; Via, L; Pérez, S; López, C; Puig Barberà, J; de la Pinta, M; Riera, M; Diez Domingo, J; Bengnér, M; Berglund, J; Blom, K; Liu, B; Pauksens, K; Rombo, L; Chen, M; Cheng, H; Hwang, S; Liu, C; Mcnally, D; Thompson, A; Andrews, C; Collins, H; Downey, H; Ervin, J; Freedman, M; Hoekstra, J; Hull, S; Levin, M; Marcadis, I; Rankin, B; Van Cleeff, M
Articolo su rivista
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/114591
Citazioni
  • ???jsp.display-item.citation.pmc??? 411
  • Scopus 953
  • ???jsp.display-item.citation.isi??? 794
social impact