In clinical trials, treatment with a combination of the nucleotide polymerase inhibitor sofosbuvir and the antiviral drug ribavirin was associated with high response rates among patients with hepatitis C virus (HCV) genotype 2 infection, with lower response rates among patients with HCV genotype 3 infection.

Zeuzem, S., Dusheiko, G., Salupere, R., Mangia, A., Flisiak, R., Hyland, R., et al. (2014). Sofosbuvir and Ribavirin in HCV genotypes 2 and 3. THE NEW ENGLAND JOURNAL OF MEDICINE, 370(21), 1993-2001 [10.1056/NEJMoa1316145].

Sofosbuvir and Ribavirin in HCV genotypes 2 and 3

Angelico, M
2014-01-01

Abstract

In clinical trials, treatment with a combination of the nucleotide polymerase inhibitor sofosbuvir and the antiviral drug ribavirin was associated with high response rates among patients with hepatitis C virus (HCV) genotype 2 infection, with lower response rates among patients with HCV genotype 3 infection.
2014
Pubblicato
Rilevanza internazionale
Articolo
Sì, ma tipo non specificato
Settore MED/12 - GASTROENTEROLOGIA
English
Con Impact Factor ISI
Adult; Aged; Antiviral Agents; Drug Resistance, Viral; Drug Therapy, Combination; Female; Genotype; Hepacivirus; Hepatitis C, Chronic; Humans; Male; Middle Aged; RNA, Viral; Ribavirin; Uridine Monophosphate; Viral Load
Zeuzem, S., Dusheiko, G., Salupere, R., Mangia, A., Flisiak, R., Hyland, R., et al. (2014). Sofosbuvir and Ribavirin in HCV genotypes 2 and 3. THE NEW ENGLAND JOURNAL OF MEDICINE, 370(21), 1993-2001 [10.1056/NEJMoa1316145].
Zeuzem, S; Dusheiko, G; Salupere, R; Mangia, A; Flisiak, R; Hyland, R; Illeperuma, A; Svarovskaia, E; Brainard, D; Symonds, W; Subramanian, G; Mchutchison, J; Weiland, O; Reesink, H; Ferenci, P; Hezode, C; Esteban, R; Valence, I; Angelico, M
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/114043
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