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To evaluate the replication capacity and phenotypic susceptibility to dolutegravir and raltegravir of wild-type and raltegravir-resistant HIV-1 strains in several cellular systems.

Pollicita, M., Surdo, M., DI SANTO, F., Cortese, M., Fabeni, L., Fedele, V., et al. (2014). Comparative replication capacity of raltegravir-resistant strains and antiviral activity of the new-generation integrase inhibitor dolutegravir in human primary macrophages and lymphocytes. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 69(9), 2412-2419 [10.1093/jac/dku144].

Comparative replication capacity of raltegravir-resistant strains and antiviral activity of the new-generation integrase inhibitor dolutegravir in human primary macrophages and lymphocytes

POLLICITA, MICHELA;DI SANTO, FABIOLA;CECCHERINI SILBERSTEIN, FRANCESCA;PERNO, CARLO FEDERICO;SVICHER, VALENTINA
2014-05-23

Abstract

To evaluate the replication capacity and phenotypic susceptibility to dolutegravir and raltegravir of wild-type and raltegravir-resistant HIV-1 strains in several cellular systems.
23-mag-2014
Pubblicato
Rilevanza internazionale
Articolo
Sì, ma tipo non specificato
Settore MED/07 - MICROBIOLOGIA E MICROBIOLOGIA CLINICA
English
HIV infection; inhibition of viral replication; primary cells; Cells, Cultured; HIV Integrase; HIV Integrase Inhibitors; HIV-1; Heterocyclic Compounds, 3-Ring; Humans; Lymphocytes; Macrophages; Microbial Sensitivity Tests; Mutant Proteins; Pyrrolidinones; Virus Replication; Drug Resistance, Viral
Pollicita, M., Surdo, M., DI SANTO, F., Cortese, M., Fabeni, L., Fedele, V., et al. (2014). Comparative replication capacity of raltegravir-resistant strains and antiviral activity of the new-generation integrase inhibitor dolutegravir in human primary macrophages and lymphocytes. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 69(9), 2412-2419 [10.1093/jac/dku144].
Pollicita, M; Surdo, M; DI SANTO, F; Cortese, M; Fabeni, L; Fedele, V; Malet, I; Marcelin, A; Calvez, V; CECCHERINI SILBERSTEIN, F; Perno, Cf; Svicher, V
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/113109
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