The clinical application of IFN-gamma release assays (IGRAs) has recently improved the diagnosis of latent tuberculosis infection. In a multicenter study of the Tuberculosis Network European Trialsgroup (TBNET) we aimed to ascertain in routine clinical practice the accuracy of a novel assay using selected peptides encoded in the mycobacterial genomic region of difference (RD) 1 for the diagnosis of active tuberculosis in comparison with tuberculin skin test (TST), QuantiFERON-TB GOLD In-Tube (Cellestis Ltd., Carnegie, Australia) and T-SPOT.TB (Oxfordimmunotec, Abingdon, UK).
Goletti, D., Carrara, S., Stefania, C., Butera, O., Amicosante, M., Ernst, M., et al. (2008). Accuracy of immunodiagnostic tests for active tuberculosis using single and combined results: a multicenter TBNET-Study. PLOS ONE, 3(10), e3417-e3417.
Tipologia: | Articolo su rivista |
Citazione: | Goletti, D., Carrara, S., Stefania, C., Butera, O., Amicosante, M., Ernst, M., et al. (2008). Accuracy of immunodiagnostic tests for active tuberculosis using single and combined results: a multicenter TBNET-Study. PLOS ONE, 3(10), e3417-e3417. |
Lingua: | English |
Settore Scientifico Disciplinare: | Settore MED/04 - Patologia Generale |
Revisione (peer review): | Esperti anonimi |
Tipo: | Articolo |
Rilevanza: | Rilevanza internazionale |
Digital Object Identifier (DOI): | http://dx.doi.org/10.1371/journal.pone.0003417 |
Stato di pubblicazione: | Pubblicato |
Data di pubblicazione: | 2008 |
Titolo: | Accuracy of immunodiagnostic tests for active tuberculosis using single and combined results: a multicenter TBNET-Study |
Autori: | |
Autori: | Goletti, D; Carrara, S; Stefania, C; Butera, O; Amicosante, M; Ernst, M; Sauzullo, I; Vullo, V; Cirillo, D; Borroni, E; Markova, R; Drenska, R; Dominguez, J; Latorre, I; Angeletti, C; Navarra, A; Petrosillo, N; Lauria, F; Ippolito, G; Migliori, G; Lange, C; Girardi, E |
Appare nelle tipologie: | 01 - Articolo su rivista |