Attention deficit/hyperactivity disorder (ADHD) is the behavioural disorder most commonly diagnosed in childhood. In addition to the main symptoms of inattention, impulsiveness and hyperactivity, neurological soft signs (NSS) are often associated with ADHD. NSS are discrete motor and sensory disorders that cannot be linked to specific cerebral lesions. We review all the scientific contributions on NSS in ADHD. The conclusions support the presence of an alteration in the neural networks for motor control inhibition, at the base of the pathophysiology of NSS in children with ADHD, as well as a possible central role of dopamine in these neural circuits.

Pasini, A., D'Agati, E. (2009). Pathophysiology of NSS in ADHD. THE WORLD JOURNAL OF BIOLOGICAL PSYCHIATRY, 10(4 Pt 2), 495-502 [10.1080/15622970902789148].

Pathophysiology of NSS in ADHD

PASINI, AUGUSTO;D'AGATI, ELISA
2009-01-01

Abstract

Attention deficit/hyperactivity disorder (ADHD) is the behavioural disorder most commonly diagnosed in childhood. In addition to the main symptoms of inattention, impulsiveness and hyperactivity, neurological soft signs (NSS) are often associated with ADHD. NSS are discrete motor and sensory disorders that cannot be linked to specific cerebral lesions. We review all the scientific contributions on NSS in ADHD. The conclusions support the presence of an alteration in the neural networks for motor control inhibition, at the base of the pathophysiology of NSS in children with ADHD, as well as a possible central role of dopamine in these neural circuits.
2009
Pubblicato
Rilevanza internazionale
Articolo
Esperti anonimi
Settore MED/39 - NEUROPSICHIATRIA INFANTILE
English
Magnetic Resonance Imaging; Animals; Humans; Brain Damage, Chronic; Neurologic Examination; Cerebellum; Disease Models, Animal; Methylphenidate; Mice; Central Nervous System Stimulants; Child; Neural Inhibition; Nerve Net; Rats; Cerebral Cortex; Dopamine; Attention Deficit Disorder with Hyperactivity; Motor Neurons
Pasini, A., D'Agati, E. (2009). Pathophysiology of NSS in ADHD. THE WORLD JOURNAL OF BIOLOGICAL PSYCHIATRY, 10(4 Pt 2), 495-502 [10.1080/15622970902789148].
Pasini, A; D'Agati, E
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/106044
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