Results of Membrane-Activated Chelator Stroke Intervention randomized trial of DP-b99 in acute ischemic stroke

Kr1, L; Bornstein, N; Diener, H; Gorelick, P; Rosenberg, G; Shuaib, A; Lees, K; Bornstein, N; Diener, H; Gorelick, P; Rosenberg, G; Shuaib, A; Fazekas, F; Ford, I; Mohr, J; Rosenberg, G; Marshall, L; Geffen, P; Bibliowicz, A; Michel, D; Rotmensch, H; Schuckelt, R; Ding, D; Soeder, T; Gatterer, A; Gruber, F; Willeit, J; Weber, J; Moro, C; Silva, G; Rocha, M; Fabio, S; Shuaib, A; Buck, B; Tomek, A; Krajickova, D; Bauer, J; Ehler, E; Vaclavik, D; Dolezil, D; Sramek, M; Skoda, O; Sablot, D; Rouanet, F; Hosseini, H; Amarenco, P; Moulin, T; Ludolph, A; Hetzel, A; Kastrup, A; Griewing, B; Hobohm, C; Weimar, C; Reinhard, C; Nabavi, D; Schneider, D; Busch, E; Scherzinger, G; Glahn, J; Faiss, J; Klingelhofer, J; Wasser, K; Groeschel, K; Kohrmann, M; Maschke, M; Von Mering, M; Seidel, G; Goertler, M; Kaminski, R; Els, T; Walter, U; Limmroth, V; Csanyi, A; Valikovics, A; Panczel, G; Csiba, L; Szegedi, N; Horvath, S; Weller, B; Tanne, D; Dorodnicov, E; Bornstein, N; Leker, R; Lampl, Y; Micieli, G; Eleopra, R; Guidetti, D; Bottacchi, E; Agnelli, G; Comi, G; Bono, G; Melis, M; Stanzione, P; Di Lazzaro, V; Schreuder, T; Stepien, A; Czlonkowska, A; Kuczynska Zardzewialy, A; Stoinski, J; Jackowski, M; Brola, W; Fryze, W; Stelmasiak, Z; Cunha, L; Melo, T; Salgado, V; Cruz, V; Savic, M; Krastev, G; Vyletelka, J; Dvorak, M; Brozman, M; Nosal, V; Kok, A; Van Dyk, C; Bester, F; Roos, J; Gardiner, J; De Vries Basson, M; Davalos, A; De La Ossa,; N,; Campello, R; Tejedor, A; E,; Masjuan, J; Fábregas, J; Serena, J; Alvarez, J; Castillo, J; Pons, J; Vivancos, J; Arenillas, J; Segura, T; Lyrer, P; Vaishnav, A; Pineda, C; Veznedaroglu, E; Mallenbaum, S

doi:10.1161/STROKEAHA.111.000013

DP-b99, a lipophilic moderate-affinity chelator of zinc, was postulated to improve recovery after acute ischemic stroke. We evaluated the safety and therapeutic effects of DP-b99 in patients with acute hemispheric ischemic stroke.

Lees, K., Bornstein, N., Diener, H., Gorelick, P., Rosenberg, G., Shuaib, A., et al. (2013). Results of Membrane-Activated Chelator Stroke Intervention randomized trial of DP-b99 in acute ischemic stroke. STROKE, 44(3), 580-584 [10.1161/STROKEAHA.111.000013].

Results of Membrane-Activated Chelator Stroke Intervention randomized trial of DP-b99 in acute ischemic stroke

Lees KR1;Bornstein N;Diener HC;Gorelick PB;Rosenberg G;Shuaib A;Lees, KR;Bornstein, N;Diener, H;Gorelick, PB;Rosenberg, G;Shuaib, A;Fazekas, F;Ford, I;Mohr, JP;Rosenberg, G;Marshall, LS;Geffen, P;Bibliowicz, A;Michel, D;Rotmensch, H;Schuckelt, R;Ding, D;Soeder, T;Gatterer, A;Gruber, F;Willeit, J;Weber, J;Moro, CH;Silva, G;Rocha, MS;Fabio, S;Shuaib, A;Buck, B;Tomek, A;Krajickova, D;Bauer, J;Ehler, E;Vaclavik, D;Dolezil, D;Sramek, M;Skoda, O;Sablot, D;Rouanet, F;Hosseini, H;Amarenco, P;Moulin, T;Ludolph, A;Hetzel, A;Kastrup, A;Griewing, B;Hobohm, C;Weimar, C;Reinhard,C;Nabavi, DG;Schneider, D;Busch, EW;Scherzinger, G;Glahn, J;Faiss, J;Klingelhofer, J;Wasser, K;Groeschel, K;Kohrmann, M;Maschke, M;Von Mering, M;Seidel, G;Goertler, M;Kaminski, RU;Els, T;Walter, U;Limmroth, V;Csanyi, A;Valikovics, A;Panczel, G;Csiba, L;Szegedi, N;Horvath, S;Weller, B;Tanne, D;Dorodnicov, E;Bornstein, N;Leker, R;Lampl, Y;Micieli, G;Eleopra, R;Guidetti, D;Bottacchi, E;Agnelli, G;Comi, G;Bono, G;Melis, M;STANZIONE, PAOLO;Di Lazzaro, V;Schreuder, T;Stepien, A;Czlonkowska, A;Kuczynska Zardzewialy, A;Stoinski, J;Jackowski, M;Brola, W;Fryze, W;Stelmasiak, Z;Cunha, L;Melo, T;Salgado, V;Cruz, V;Savic, M;Krastev, G;Vyletelka, J;Dvorak, M;Brozman, M;Nosal, V;Kok, A;Van Dyk, C;Bester, FC;Roos, JS;Gardiner, J;De Vries Basson, MM;Davalos, A;de la Ossa;N;Rodríguez Campello;A, Tejedor;E;Masjuan, J;Fábregas, J;Serena, J;Alvarez, J;Castillo, J;Pons, J;Vivancos, J;Arenillas, J;Segura, T;Lyrer, P;Vaishnav, A;Pineda, C;Veznedaroglu, E;Mallenbaum, S.

2013-03-01

Abstract

DP-b99, a lipophilic moderate-affinity chelator of zinc, was postulated to improve recovery after acute ischemic stroke. We evaluated the safety and therapeutic effects of DP-b99 in patients with acute hemispheric ischemic stroke.

Scheda breve

Scheda completa

Scheda completa (DC)

	Data di pubblicazione
	
				mar-2013
			
	Status di pubblicazione
	
				Pubblicato
			
	DOI dell'articolo
	
				https://dx.doi.org/10.1161/STROKEAHA.111.000013
			
	Rilevanza
	
				Rilevanza internazionale
			
	Tipo
	
				Articolo
			
	Referee
	
				Sì, ma tipo non specificato
			
	Settore disciplinare dell'articolo (valido fino a 24/06/2024)
	
				Settore MED/26 - NEUROLOGIA
			
	Lingua del contenuto
	
				English
			
	Parole chiave
	
				Severity of Illness Index; Egtazic Acid; Double-Blind Method; Endpoint Determination; Dose-Response Relationship, Drug; Humans; Stroke; Aged; Administration, Intravenous; Aged, 80 and over; Treatment Outcome; Middle Aged; Chelating Agents; Time Factors; Female; Male
			
	Citazione
	
				Lees, K., Bornstein, N., Diener, H., Gorelick, P., Rosenberg, G., Shuaib, A., et al. (2013). Results of Membrane-Activated Chelator Stroke Intervention randomized trial of DP-b99 in acute ischemic stroke. STROKE, 44(3), 580-584 [10.1161/STROKEAHA.111.000013].
			
	Tutti gli autori
	
						Lees, K; Bornstein, N; Diener, H; Gorelick, P; Rosenberg, G; Shuaib, A; Lees, K; Bornstein, N; Diener, H; Gorelick, P; Rosenberg, G; Shuaib, A; Fazeka...espandi
						
	Tipologia
	
				Articolo su rivista
			
	Appare nelle tipologie:
	
				01 - Articolo su rivista

File in questo prodotto:

Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/103651

Citazioni

11

26

27

Results of Membrane-Activated Chelator Stroke Intervention randomized trial of DP-b99 in acute ischemic stroke

2013-03-01

Abstract

Scheda breve Scheda completa Scheda completa (DC)

Informazioni

Citazioni

social impact

Conferma cancellazione

Scheda breve

Scheda completa

Scheda completa (DC)