In vitro study showed that NADPH oxidase (NOx), the most important enzyme producing reactive oxygen species (ROS), plays a role in the process of platelet activation. However, it is unclear if changes in its activity affect platelet activation in vivo.

Carnevale, R., Loffredo, L., Sanguigni, V., Plebani, A., Rossi, P., Pignata, C., et al. (2014). Different degrees of NADPH oxidase 2 regulation and in vivo platelet activation: lesson from chronic granulomatous disease. JOURNAL OF THE AMERICAN HEART ASSOCIATION. CARDIOVASCULAR AND CEREBROVASCULAR DISEASE, 3(3), e000920-e000920 [10.1161/JAHA.114.000920].

Different degrees of NADPH oxidase 2 regulation and in vivo platelet activation: lesson from chronic granulomatous disease

SANGUIGNI, VALERIO;ROSSI, PAOLO;FINOCCHI, ANDREA;
2014-06-01

Abstract

In vitro study showed that NADPH oxidase (NOx), the most important enzyme producing reactive oxygen species (ROS), plays a role in the process of platelet activation. However, it is unclear if changes in its activity affect platelet activation in vivo.
giu-2014
Pubblicato
Rilevanza internazionale
Articolo
Sì, ma tipo non specificato
Settore MED/09 - MEDICINA INTERNA
English
Con Impact Factor ISI
platelet activation; NOx2; X‐CGD; oxidative stress
Carnevale, R., Loffredo, L., Sanguigni, V., Plebani, A., Rossi, P., Pignata, C., et al. (2014). Different degrees of NADPH oxidase 2 regulation and in vivo platelet activation: lesson from chronic granulomatous disease. JOURNAL OF THE AMERICAN HEART ASSOCIATION. CARDIOVASCULAR AND CEREBROVASCULAR DISEASE, 3(3), e000920-e000920 [10.1161/JAHA.114.000920].
Carnevale, R; Loffredo, L; Sanguigni, V; Plebani, A; Rossi, P; Pignata, C; Martire, B; Finocchi, A; Pietrogrande, M; Azzari, C; Soresina, A; Martino, ...espandi
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/100780
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