POMELLA, SILVIA
POMELLA, SILVIA
Dipartimento di Scienze cliniche e Medicina Traslazionale
CDK9 as a Valuable Target in Cancer: From Natural Compounds Inhibitors to Current Treatment in Pediatric Soft Tissue Sarcomas
2020-01-01 Cassandri, M; Fioravanti, R; Pomella, S; Valente, S; Rotili, D; Del Baldo, G; De Angelis, B; Rota, R; Mai, A
Chemical genomics reveals histone deacetylases are required for core regulatory transcription
2019-01-01 Gryder, Be; Wu, L; Woldemichael, Gm; Pomella, S; Quinn, Tr; Park, Pmc; Cleveland, A; Stanton, Bz; Song, Y; Rota, R; Wiest, O; Yohe, Me; Shern, Jf; Qi, J; Khan, J
Design of First-in-Class Dual {EZH}2/{HDAC} Inhibitor: biochemical activity and biological evaluation in cancer cells
2020-01-01 Romanelli, A; Stazi, G; Fioravanti, R; Zwergel, C; Di Bello, E; Pomella, S; Perrone, C; Battistelli, C; Strippoli, R; Tripodi, M; del Bufalo, D; Rota, R; Trisciuoglio, D; Mai, A; Valente, S
DNMT3A and DNMT3B Targeting as an Effective Radiosensitizing Strategy in Embryonal Rhabdomyosarcoma
2021-01-01 Camero, S; Vitali, G; Pontecorvi, P; Ceccarelli, S; Anastasiadou, E; Cicchetti, F; Flex, E; Pomella, S; Cassandri, M; R, R; Marampon, F; Marchese, C; Schiavetti, A; Megiorni, F
Dose-dependent activation of gene expression is achieved using CRISPR and small molecules that recruit endogenous chromatin machinery
2019-01-01 Chiarella, Am; Butler, Kv; Gryder, Be; Lu, D; Wang, Ta; Yu, X; Pomella, S; Khan, J; Jin, J; Hathaway, Na
Epigenetic remodelling in human hepatocellular carcinoma
2022-01-01 Braghini, Mr; Lo Re, O; Romito, I; Fernandez-Barrena, Mg; Barbaro, B; Pomella, S; Rota, R; Vinciguerra, M; Avila, Ma; Alisi, A
FAK Signaling in Rhabdomyosarcoma
2020-01-01 Perrone, C; Pomella, S; Cassandri, M; Rita Braghini, M; Pezzella, M; Locatelli, F; Rota, R
Focal adhesion kinase inhibitor TAE226 combined with Sorafenib slows down hepatocellular carcinoma by multiple epigenetic effects
2021-01-01 Romito, I; Porru, M; Braghini, Mr; Pompili, L; Panera, N; Crudele, A; Gnani, D; De Stefanis, C; Scarsella, M; Pomella, S; Levi Mortera, S; de Billy, E; Conti, Al; Marzano, V; Putignani, L; Vinciguerra, M; Balsano, C; Pastore, A; Rota, R; Tartaglia, M; Leonetti, C; Alisi, A
Histone hyperacetylation disrupts core gene regulatory architecture in rhabdomyosarcoma
2019-11-29 Gryder, Be; Pomella, S; Sayers, C; Wu, Xs; Song, Y; Chiarella, Am; Bagchi, S; Chou, H; Sinniah, Rs; Walton, A; Wen, X; Rota, R; Hathaway, Na; Zhao, K; Chen, J; Vakoc, Cr; Shern, Jf; Stanton, Bz; Khan, J
In vitro and in vivo single-agent efficacy of checkpoint kinase inhibition in acute lymphoblastic leukemia
2015-01-01 Iacobucci, I; Di Ror(`a), Agl; Falzacappa, Mvv; Agostinelli, C; Derenzini, E; Ferrari, A; Papayannidis, C; Lonetti, A; Righi, S; Imbrogno, E; Pomella, S; Venturi, C; Guadagnuolo, V; Cattina, F; Ottaviani, E; Abbenante, Mc; Vitale, A; Elia, L; Russo, D; Zinzani, Pl; Pileri, S; Pelicci, Pg; Martinelli, G
Interaction between SNAI2 and MYOD enhances oncogenesis and suppresses differentiation in Fusion Negative Rhabdomyosarcoma
2021-01-01 Pomella, S; Sreenivas, P; Gryder, Be; Wang, L; Milewski, D; Cassandri, M; Baxi, K; Hensch, Nr; Carcarino, E; Song, Y; Chou, H; Yohe, Me; Stanton, Bz; Amadio, B; Caruana, I; De Stefanis, C; De Vito, R; Locatelli, F; Chen, Y; Chen, Ey; Houghton, P; Khan, J; Rota, R; Ignatius, Ms
MET inhibition sensitizes rhabdomyosarcoma cells to NOTCH signaling suppression
2022-01-01 Perrone, C; Pomella, S; Cassandri, M; Pezzella, M; Milano, Gm; Colletti, M; Cossetti, C; Pericoli, G; Di Giannatale, A; de Billy, E; Vinci, M; Petrini, S; Marampon, F; Quintarelli, C; Taulli, R; Roma, J; Gallego, S; Camero, S; Mariottini, P; Cervelli, M; Maestro, R; Miele, L; De Angelis, B; Locatelli, F; Rota, R
MicroRNA-101 is repressed by EZH2 and its restoration inhibits tumorigenic features in embryonal rhabdomyosarcoma
2015-01-01 Vella, S; Pomella, S; Leoncini, Pp; Colletti, M; Conti, B; Marquez, Ve; Strillacci, A; Roma, J; Gallego, S; Milano, Gm; Capogrossi, Mc; Bertaina, A; Ciarapica, R; Rota, R
Miswired Enhancer Logic Drives a Cancer of the Muscle Lineage
2020-01-01 Gryder, Be; Wachtel, M; Chang, K; El Demerdash, O; Aboreden, Ng; Mohammed, W; Ewert, W; Pomella, S; Rota, R; Wei, Js; Song, Y; Stanton, Bz; Schafer, B; Vakoc, Cr; Khan, J
MS-275 (Entinostat) Promotes Radio-Sensitivity in PAX3-FOXO1 Rhabdomyosarcoma Cells
2021-01-01 Cassandri, M; Pomella, S; Rossetti, A; Petragnano, F; Milazzo, L; Vulcano, F; Camero, S; Codenotti, S; Cicchetti, F; Maggio, R; Festuccia, C; Luca Gravina, G; Fanzani, A; Megiorni, F; Catanoso, M; Marchese, C; Tombolini, V; Locatelli, F; Rota, R; Marampon, F
New Insights on the Nuclear Functions and Targeting of FAK in Cancer
2022-01-01 Pomella, S; Cassandri, M; Rita Braghini, M; Marampon, F; Alisi, A; R, R
Novel non-covalent LSD1 inhibitors endowed with anticancer effects in leukemia and solid tumor cellular models
2022-01-01 Menna, M; Fiorentino, F; Marrocco, B; Lucidi, A; Tomassi, S; Cilli, D; Romanenghi, M; Cassandri, M; Pomella, S; Pezzella, M; Del Bufalo, D; Salik Zeya Ansari, M; Toma( (s))evi('(c)), N; Mladenovi('(c)), M; Viviano, M; Sbardella, G; Rota, R; Trisciuoglio, D; Minucci, S; Mattevi, A; Rotili, D; Mai, A
PAX3-FOXO1 establishes myogenic super enhancers and confers BET bromodomain vulnerability
2017-01-01 Gryder, Be; Yohe, Me; Chou, H-; Zhang, X; Marques, J; Wachtel, M; Schaefer, B; Sen, N; Song, Y; Gualtieri, A; Pomella, S; Rota, R; Cleveland, A; Wen, X; Sindiri, S; Wei, Js; Barr, Fg; Das, S; Andresson, T; Guha, R; Lal-Nag, M; Ferrer, M; Shern, Jf; Zhao, K; Thomas, Cj; Khan, J
Radioresistance in rhabdomyosarcomas: much more than a question of dose
2022-09-29 Camero, S; Cassandri, M; Pomella, S; Milazzo, L; Vulcano, F; Porrazzo, A; Barillari, G; Marchese, C; Codenotti, S; Tomaciello, M; Rota, R; Fanzani, A; Megiorni, F; Marampon, F
Romidepsin (FK228) fails in counteracting the transformed phenotype of rhabdomyosarcoma cells but efficiently radiosensitizes, in vitro and in vivo, the alveolar phenotype subtype
2021-01-01 Rossetti, A; Petragnano, F; Milazzo, L; Vulcano, F; Macioce, G; Codenotti, S; Cassandri, M; Pomella, S; Cicchetti, F; Fasciani, I; Antinozzi, C; Di Luigi, L; Festuccia, C; De Felice, F; Vergine, M; Fanzani, A; Rota, R; Maggio, R; Polimeni, A; Tombolini, V; Gravina, Gl; Marampon, F
Data di pubblicazione | Titolo | Autore(i) | Tipo | File |
---|---|---|---|---|
1-gen-2020 | CDK9 as a Valuable Target in Cancer: From Natural Compounds Inhibitors to Current Treatment in Pediatric Soft Tissue Sarcomas | Cassandri, M; Fioravanti, R; Pomella, S; Valente, S; Rotili, D; Del Baldo, G; De Angelis, B; Rota, R; Mai, A | Articolo su rivista | |
1-gen-2019 | Chemical genomics reveals histone deacetylases are required for core regulatory transcription | Gryder, Be; Wu, L; Woldemichael, Gm; Pomella, S; Quinn, Tr; Park, Pmc; Cleveland, A; Stanton, Bz; Song, Y; Rota, R; Wiest, O; Yohe, Me; Shern, Jf; Qi, J; Khan, J | Articolo su rivista | |
1-gen-2020 | Design of First-in-Class Dual {EZH}2/{HDAC} Inhibitor: biochemical activity and biological evaluation in cancer cells | Romanelli, A; Stazi, G; Fioravanti, R; Zwergel, C; Di Bello, E; Pomella, S; Perrone, C; Battistelli, C; Strippoli, R; Tripodi, M; del Bufalo, D; Rota, R; Trisciuoglio, D; Mai, A; Valente, S | Articolo su rivista | |
1-gen-2021 | DNMT3A and DNMT3B Targeting as an Effective Radiosensitizing Strategy in Embryonal Rhabdomyosarcoma | Camero, S; Vitali, G; Pontecorvi, P; Ceccarelli, S; Anastasiadou, E; Cicchetti, F; Flex, E; Pomella, S; Cassandri, M; R, R; Marampon, F; Marchese, C; Schiavetti, A; Megiorni, F | Articolo su rivista | |
1-gen-2019 | Dose-dependent activation of gene expression is achieved using CRISPR and small molecules that recruit endogenous chromatin machinery | Chiarella, Am; Butler, Kv; Gryder, Be; Lu, D; Wang, Ta; Yu, X; Pomella, S; Khan, J; Jin, J; Hathaway, Na | Articolo su rivista | |
1-gen-2022 | Epigenetic remodelling in human hepatocellular carcinoma | Braghini, Mr; Lo Re, O; Romito, I; Fernandez-Barrena, Mg; Barbaro, B; Pomella, S; Rota, R; Vinciguerra, M; Avila, Ma; Alisi, A | Articolo su rivista | |
1-gen-2020 | FAK Signaling in Rhabdomyosarcoma | Perrone, C; Pomella, S; Cassandri, M; Rita Braghini, M; Pezzella, M; Locatelli, F; Rota, R | Articolo su rivista | |
1-gen-2021 | Focal adhesion kinase inhibitor TAE226 combined with Sorafenib slows down hepatocellular carcinoma by multiple epigenetic effects | Romito, I; Porru, M; Braghini, Mr; Pompili, L; Panera, N; Crudele, A; Gnani, D; De Stefanis, C; Scarsella, M; Pomella, S; Levi Mortera, S; de Billy, E; Conti, Al; Marzano, V; Putignani, L; Vinciguerra, M; Balsano, C; Pastore, A; Rota, R; Tartaglia, M; Leonetti, C; Alisi, A | Articolo su rivista | |
29-nov-2019 | Histone hyperacetylation disrupts core gene regulatory architecture in rhabdomyosarcoma | Gryder, Be; Pomella, S; Sayers, C; Wu, Xs; Song, Y; Chiarella, Am; Bagchi, S; Chou, H; Sinniah, Rs; Walton, A; Wen, X; Rota, R; Hathaway, Na; Zhao, K; Chen, J; Vakoc, Cr; Shern, Jf; Stanton, Bz; Khan, J | Articolo su rivista | |
1-gen-2015 | In vitro and in vivo single-agent efficacy of checkpoint kinase inhibition in acute lymphoblastic leukemia | Iacobucci, I; Di Ror(`a), Agl; Falzacappa, Mvv; Agostinelli, C; Derenzini, E; Ferrari, A; Papayannidis, C; Lonetti, A; Righi, S; Imbrogno, E; Pomella, S; Venturi, C; Guadagnuolo, V; Cattina, F; Ottaviani, E; Abbenante, Mc; Vitale, A; Elia, L; Russo, D; Zinzani, Pl; Pileri, S; Pelicci, Pg; Martinelli, G | Articolo su rivista | |
1-gen-2021 | Interaction between SNAI2 and MYOD enhances oncogenesis and suppresses differentiation in Fusion Negative Rhabdomyosarcoma | Pomella, S; Sreenivas, P; Gryder, Be; Wang, L; Milewski, D; Cassandri, M; Baxi, K; Hensch, Nr; Carcarino, E; Song, Y; Chou, H; Yohe, Me; Stanton, Bz; Amadio, B; Caruana, I; De Stefanis, C; De Vito, R; Locatelli, F; Chen, Y; Chen, Ey; Houghton, P; Khan, J; Rota, R; Ignatius, Ms | Articolo su rivista | |
1-gen-2022 | MET inhibition sensitizes rhabdomyosarcoma cells to NOTCH signaling suppression | Perrone, C; Pomella, S; Cassandri, M; Pezzella, M; Milano, Gm; Colletti, M; Cossetti, C; Pericoli, G; Di Giannatale, A; de Billy, E; Vinci, M; Petrini, S; Marampon, F; Quintarelli, C; Taulli, R; Roma, J; Gallego, S; Camero, S; Mariottini, P; Cervelli, M; Maestro, R; Miele, L; De Angelis, B; Locatelli, F; Rota, R | Articolo su rivista | |
1-gen-2015 | MicroRNA-101 is repressed by EZH2 and its restoration inhibits tumorigenic features in embryonal rhabdomyosarcoma | Vella, S; Pomella, S; Leoncini, Pp; Colletti, M; Conti, B; Marquez, Ve; Strillacci, A; Roma, J; Gallego, S; Milano, Gm; Capogrossi, Mc; Bertaina, A; Ciarapica, R; Rota, R | Articolo su rivista | |
1-gen-2020 | Miswired Enhancer Logic Drives a Cancer of the Muscle Lineage | Gryder, Be; Wachtel, M; Chang, K; El Demerdash, O; Aboreden, Ng; Mohammed, W; Ewert, W; Pomella, S; Rota, R; Wei, Js; Song, Y; Stanton, Bz; Schafer, B; Vakoc, Cr; Khan, J | Articolo su rivista | |
1-gen-2021 | MS-275 (Entinostat) Promotes Radio-Sensitivity in PAX3-FOXO1 Rhabdomyosarcoma Cells | Cassandri, M; Pomella, S; Rossetti, A; Petragnano, F; Milazzo, L; Vulcano, F; Camero, S; Codenotti, S; Cicchetti, F; Maggio, R; Festuccia, C; Luca Gravina, G; Fanzani, A; Megiorni, F; Catanoso, M; Marchese, C; Tombolini, V; Locatelli, F; Rota, R; Marampon, F | Articolo su rivista | |
1-gen-2022 | New Insights on the Nuclear Functions and Targeting of FAK in Cancer | Pomella, S; Cassandri, M; Rita Braghini, M; Marampon, F; Alisi, A; R, R | Articolo su rivista | |
1-gen-2022 | Novel non-covalent LSD1 inhibitors endowed with anticancer effects in leukemia and solid tumor cellular models | Menna, M; Fiorentino, F; Marrocco, B; Lucidi, A; Tomassi, S; Cilli, D; Romanenghi, M; Cassandri, M; Pomella, S; Pezzella, M; Del Bufalo, D; Salik Zeya Ansari, M; Toma( (s))evi('(c)), N; Mladenovi('(c)), M; Viviano, M; Sbardella, G; Rota, R; Trisciuoglio, D; Minucci, S; Mattevi, A; Rotili, D; Mai, A | Articolo su rivista | |
1-gen-2017 | PAX3-FOXO1 establishes myogenic super enhancers and confers BET bromodomain vulnerability | Gryder, Be; Yohe, Me; Chou, H-; Zhang, X; Marques, J; Wachtel, M; Schaefer, B; Sen, N; Song, Y; Gualtieri, A; Pomella, S; Rota, R; Cleveland, A; Wen, X; Sindiri, S; Wei, Js; Barr, Fg; Das, S; Andresson, T; Guha, R; Lal-Nag, M; Ferrer, M; Shern, Jf; Zhao, K; Thomas, Cj; Khan, J | Articolo su rivista | |
29-set-2022 | Radioresistance in rhabdomyosarcomas: much more than a question of dose | Camero, S; Cassandri, M; Pomella, S; Milazzo, L; Vulcano, F; Porrazzo, A; Barillari, G; Marchese, C; Codenotti, S; Tomaciello, M; Rota, R; Fanzani, A; Megiorni, F; Marampon, F | Articolo su rivista | |
1-gen-2021 | Romidepsin (FK228) fails in counteracting the transformed phenotype of rhabdomyosarcoma cells but efficiently radiosensitizes, in vitro and in vivo, the alveolar phenotype subtype | Rossetti, A; Petragnano, F; Milazzo, L; Vulcano, F; Macioce, G; Codenotti, S; Cassandri, M; Pomella, S; Cicchetti, F; Fasciani, I; Antinozzi, C; Di Luigi, L; Festuccia, C; De Felice, F; Vergine, M; Fanzani, A; Rota, R; Maggio, R; Polimeni, A; Tombolini, V; Gravina, Gl; Marampon, F | Articolo su rivista |