POMELLA, SILVIA
POMELLA, SILVIA
Dipartimento di Scienze cliniche e Medicina Traslazionale
CDK9 as a Valuable Target in Cancer: From Natural Compounds Inhibitors to Current Treatment in Pediatric Soft Tissue Sarcomas
2020-01-01 Cassandri, M; Fioravanti, R; Pomella, S; Valente, S; Rotili, D; Del Baldo, G; De Angelis, B; Rota, R; Mai, A
Chemical genomics reveals histone deacetylases are required for core regulatory transcription
2019-01-01 Gryder, Be; Wu, L; Woldemichael, Gm; Pomella, S; Quinn, Tr; Park, Pmc; Cleveland, A; Stanton, Bz; Song, Y; Rota, R; Wiest, O; Yohe, Me; Shern, Jf; Qi, J; Khan, J
Design of First-in-Class Dual {EZH}2/{HDAC} Inhibitor: biochemical activity and biological evaluation in cancer cells
2020-01-01 Romanelli, A; Stazi, G; Fioravanti, R; Zwergel, C; Di Bello, E; Pomella, S; Perrone, C; Battistelli, C; Strippoli, R; Tripodi, M; del Bufalo, D; Rota, R; Trisciuoglio, D; Mai, A; Valente, S
DNA Damage Response Gene Signature as Potential Treatment Markers for Oral Squamous Cell Carcinoma
2023-01-31 Pomella, S; Cassandri, M; Melaiu, O; Marampon, F; Gargari, M; Campanella, V; Rota, R; Barillari, G
DNMT3A and DNMT3B Targeting as an Effective Radiosensitizing Strategy in Embryonal Rhabdomyosarcoma
2021-01-01 Camero, S; Vitali, G; Pontecorvi, P; Ceccarelli, S; Anastasiadou, E; Cicchetti, F; Flex, E; Pomella, S; Cassandri, M; R, R; Marampon, F; Marchese, C; Schiavetti, A; Megiorni, F
Dose-dependent activation of gene expression is achieved using CRISPR and small molecules that recruit endogenous chromatin machinery
2019-01-01 Chiarella, Am; Butler, Kv; Gryder, Be; Lu, D; Wang, Ta; Yu, X; Pomella, S; Khan, J; Jin, J; Hathaway, Na
Epigenetic remodelling in human hepatocellular carcinoma
2022-01-01 Braghini, Mr; Lo Re, O; Romito, I; Fernandez-Barrena, Mg; Barbaro, B; Pomella, S; Rota, R; Vinciguerra, M; Avila, Ma; Alisi, A
FAK Signaling in Rhabdomyosarcoma
2020-01-01 Perrone, C; Pomella, S; Cassandri, M; Rita Braghini, M; Pezzella, M; Locatelli, F; Rota, R
Focal adhesion kinase inhibitor TAE226 combined with Sorafenib slows down hepatocellular carcinoma by multiple epigenetic effects
2021-01-01 Romito, I; Porru, M; Braghini, Mr; Pompili, L; Panera, N; Crudele, A; Gnani, D; De Stefanis, C; Scarsella, M; Pomella, S; Levi Mortera, S; de Billy, E; Conti, Al; Marzano, V; Putignani, L; Vinciguerra, M; Balsano, C; Pastore, A; Rota, R; Tartaglia, M; Leonetti, C; Alisi, A
Genomic and Epigenetic Changes Drive Aberrant Skeletal Muscle Differentiation in Rhabdomyosarcoma
2023-05-18 Pomella, S; Danielli, Sg; Alaggio, R; Breunis, Wb; Hamed, E; Selfe, J; Wachtel, M; Walters, Zs; Schäfer, Bw; Rota, R; Shipley, Jm; Hettmer, S
Histone hyperacetylation disrupts core gene regulatory architecture in rhabdomyosarcoma
2019-11-29 Gryder, Be; Pomella, S; Sayers, C; Wu, Xs; Song, Y; Chiarella, Am; Bagchi, S; Chou, H; Sinniah, Rs; Walton, A; Wen, X; Rota, R; Hathaway, Na; Zhao, K; Chen, J; Vakoc, Cr; Shern, Jf; Stanton, Bz; Khan, J
In vitro and in vivo single-agent efficacy of checkpoint kinase inhibition in acute lymphoblastic leukemia
2015-01-01 Iacobucci, I; Di Ror(`a), Agl; Falzacappa, Mvv; Agostinelli, C; Derenzini, E; Ferrari, A; Papayannidis, C; Lonetti, A; Righi, S; Imbrogno, E; Pomella, S; Venturi, C; Guadagnuolo, V; Cattina, F; Ottaviani, E; Abbenante, Mc; Vitale, A; Elia, L; Russo, D; Zinzani, Pl; Pileri, S; Pelicci, Pg; Martinelli, G
Interaction between SNAI2 and MYOD enhances oncogenesis and suppresses differentiation in Fusion Negative Rhabdomyosarcoma
2021-01-01 Pomella, S; Sreenivas, P; Gryder, Be; Wang, L; Milewski, D; Cassandri, M; Baxi, K; Hensch, Nr; Carcarino, E; Song, Y; Chou, H; Yohe, Me; Stanton, Bz; Amadio, B; Caruana, I; De Stefanis, C; De Vito, R; Locatelli, F; Chen, Y; Chen, Ey; Houghton, P; Khan, J; Rota, R; Ignatius, Ms
MET inhibition sensitizes rhabdomyosarcoma cells to NOTCH signaling suppression
2022-01-01 Perrone, C; Pomella, S; Cassandri, M; Pezzella, M; Milano, Gm; Colletti, M; Cossetti, C; Pericoli, G; Di Giannatale, A; de Billy, E; Vinci, M; Petrini, S; Marampon, F; Quintarelli, C; Taulli, R; Roma, J; Gallego, S; Camero, S; Mariottini, P; Cervelli, M; Maestro, R; Miele, L; De Angelis, B; Locatelli, F; Rota, R
MicroRNA-101 is repressed by EZH2 and its restoration inhibits tumorigenic features in embryonal rhabdomyosarcoma
2015-01-01 Vella, S; Pomella, S; Leoncini, Pp; Colletti, M; Conti, B; Marquez, Ve; Strillacci, A; Roma, J; Gallego, S; Milano, Gm; Capogrossi, Mc; Bertaina, A; Ciarapica, R; Rota, R
Miswired Enhancer Logic Drives a Cancer of the Muscle Lineage
2020-01-01 Gryder, Be; Wachtel, M; Chang, K; El Demerdash, O; Aboreden, Ng; Mohammed, W; Ewert, W; Pomella, S; Rota, R; Wei, Js; Song, Y; Stanton, Bz; Schafer, B; Vakoc, Cr; Khan, J
MS-275 (Entinostat) Promotes Radio-Sensitivity in PAX3-FOXO1 Rhabdomyosarcoma Cells
2021-01-01 Cassandri, M; Pomella, S; Rossetti, A; Petragnano, F; Milazzo, L; Vulcano, F; Camero, S; Codenotti, S; Cicchetti, F; Maggio, R; Festuccia, C; Luca Gravina, G; Fanzani, A; Megiorni, F; Catanoso, M; Marchese, C; Tombolini, V; Locatelli, F; Rota, R; Marampon, F
MYOD-SKP2 axis boosts tumorigenesis in fusion negative rhabdomyosarcoma by preventing differentiation through p57Kip2 targeting
2023-12-15 Pomella, S; Cassandri, M; D'Archivio, L; Porrazzo, A; Cossetti, C; Phelps, D; Perrone, C; Pezzella, M; Cardinale, A; Wachtel, M; Aloisi, S; Milewski, D; Colletti, M; Sreenivas, P; Walters, Zs; Barillari, G; Di Giannatale, A; Milano, Gm; De Stefanis, C; Alaggio, R; Rodriguez-Rodriguez, S; Carlesso, N; Vakoc, Cr; Velardi, E; Schafer, Bw; Guccione, E; Gatz, Sa; Wasti, A; Yohe, M; Ignatius, M; Quintarelli, C; Shipley, J; Miele, L; Khan, J; Houghton, Pj; Marampon, F; Gryder, Be; De Angelis, B; Locatelli, F; Rota, R
New Insights on the Nuclear Functions and Targeting of FAK in Cancer
2022-01-01 Pomella, S; Cassandri, M; Rita Braghini, M; Marampon, F; Alisi, A; R, R
PAX3-FOXO1 establishes myogenic super enhancers and confers BET bromodomain vulnerability
2017-01-01 Gryder, Be; Yohe, Me; Chou, H-; Zhang, X; Marques, J; Wachtel, M; Schaefer, B; Sen, N; Song, Y; Gualtieri, A; Pomella, S; Rota, R; Cleveland, A; Wen, X; Sindiri, S; Wei, Js; Barr, Fg; Das, S; Andresson, T; Guha, R; Lal-Nag, M; Ferrer, M; Shern, Jf; Zhao, K; Thomas, Cj; Khan, J
| Data di pubblicazione | Titolo | Autore(i) | Tipo | File |
|---|---|---|---|---|
| 1-gen-2020 | CDK9 as a Valuable Target in Cancer: From Natural Compounds Inhibitors to Current Treatment in Pediatric Soft Tissue Sarcomas | Cassandri, M; Fioravanti, R; Pomella, S; Valente, S; Rotili, D; Del Baldo, G; De Angelis, B; Rota, R; Mai, A | Articolo su rivista | |
| 1-gen-2019 | Chemical genomics reveals histone deacetylases are required for core regulatory transcription | Gryder, Be; Wu, L; Woldemichael, Gm; Pomella, S; Quinn, Tr; Park, Pmc; Cleveland, A; Stanton, Bz; Song, Y; Rota, R; Wiest, O; Yohe, Me; Shern, Jf; Qi, J; Khan, J | Articolo su rivista | |
| 1-gen-2020 | Design of First-in-Class Dual {EZH}2/{HDAC} Inhibitor: biochemical activity and biological evaluation in cancer cells | Romanelli, A; Stazi, G; Fioravanti, R; Zwergel, C; Di Bello, E; Pomella, S; Perrone, C; Battistelli, C; Strippoli, R; Tripodi, M; del Bufalo, D; Rota, R; Trisciuoglio, D; Mai, A; Valente, S | Articolo su rivista | |
| 31-gen-2023 | DNA Damage Response Gene Signature as Potential Treatment Markers for Oral Squamous Cell Carcinoma | Pomella, S; Cassandri, M; Melaiu, O; Marampon, F; Gargari, M; Campanella, V; Rota, R; Barillari, G | Articolo su rivista | |
| 1-gen-2021 | DNMT3A and DNMT3B Targeting as an Effective Radiosensitizing Strategy in Embryonal Rhabdomyosarcoma | Camero, S; Vitali, G; Pontecorvi, P; Ceccarelli, S; Anastasiadou, E; Cicchetti, F; Flex, E; Pomella, S; Cassandri, M; R, R; Marampon, F; Marchese, C; Schiavetti, A; Megiorni, F | Articolo su rivista | |
| 1-gen-2019 | Dose-dependent activation of gene expression is achieved using CRISPR and small molecules that recruit endogenous chromatin machinery | Chiarella, Am; Butler, Kv; Gryder, Be; Lu, D; Wang, Ta; Yu, X; Pomella, S; Khan, J; Jin, J; Hathaway, Na | Articolo su rivista | |
| 1-gen-2022 | Epigenetic remodelling in human hepatocellular carcinoma | Braghini, Mr; Lo Re, O; Romito, I; Fernandez-Barrena, Mg; Barbaro, B; Pomella, S; Rota, R; Vinciguerra, M; Avila, Ma; Alisi, A | Articolo su rivista | |
| 1-gen-2020 | FAK Signaling in Rhabdomyosarcoma | Perrone, C; Pomella, S; Cassandri, M; Rita Braghini, M; Pezzella, M; Locatelli, F; Rota, R | Articolo su rivista | |
| 1-gen-2021 | Focal adhesion kinase inhibitor TAE226 combined with Sorafenib slows down hepatocellular carcinoma by multiple epigenetic effects | Romito, I; Porru, M; Braghini, Mr; Pompili, L; Panera, N; Crudele, A; Gnani, D; De Stefanis, C; Scarsella, M; Pomella, S; Levi Mortera, S; de Billy, E; Conti, Al; Marzano, V; Putignani, L; Vinciguerra, M; Balsano, C; Pastore, A; Rota, R; Tartaglia, M; Leonetti, C; Alisi, A | Articolo su rivista | |
| 18-mag-2023 | Genomic and Epigenetic Changes Drive Aberrant Skeletal Muscle Differentiation in Rhabdomyosarcoma | Pomella, S; Danielli, Sg; Alaggio, R; Breunis, Wb; Hamed, E; Selfe, J; Wachtel, M; Walters, Zs; Schäfer, Bw; Rota, R; Shipley, Jm; Hettmer, S | Articolo su rivista | |
| 29-nov-2019 | Histone hyperacetylation disrupts core gene regulatory architecture in rhabdomyosarcoma | Gryder, Be; Pomella, S; Sayers, C; Wu, Xs; Song, Y; Chiarella, Am; Bagchi, S; Chou, H; Sinniah, Rs; Walton, A; Wen, X; Rota, R; Hathaway, Na; Zhao, K; Chen, J; Vakoc, Cr; Shern, Jf; Stanton, Bz; Khan, J | Articolo su rivista | |
| 1-gen-2015 | In vitro and in vivo single-agent efficacy of checkpoint kinase inhibition in acute lymphoblastic leukemia | Iacobucci, I; Di Ror(`a), Agl; Falzacappa, Mvv; Agostinelli, C; Derenzini, E; Ferrari, A; Papayannidis, C; Lonetti, A; Righi, S; Imbrogno, E; Pomella, S; Venturi, C; Guadagnuolo, V; Cattina, F; Ottaviani, E; Abbenante, Mc; Vitale, A; Elia, L; Russo, D; Zinzani, Pl; Pileri, S; Pelicci, Pg; Martinelli, G | Articolo su rivista | |
| 1-gen-2021 | Interaction between SNAI2 and MYOD enhances oncogenesis and suppresses differentiation in Fusion Negative Rhabdomyosarcoma | Pomella, S; Sreenivas, P; Gryder, Be; Wang, L; Milewski, D; Cassandri, M; Baxi, K; Hensch, Nr; Carcarino, E; Song, Y; Chou, H; Yohe, Me; Stanton, Bz; Amadio, B; Caruana, I; De Stefanis, C; De Vito, R; Locatelli, F; Chen, Y; Chen, Ey; Houghton, P; Khan, J; Rota, R; Ignatius, Ms | Articolo su rivista | |
| 1-gen-2022 | MET inhibition sensitizes rhabdomyosarcoma cells to NOTCH signaling suppression | Perrone, C; Pomella, S; Cassandri, M; Pezzella, M; Milano, Gm; Colletti, M; Cossetti, C; Pericoli, G; Di Giannatale, A; de Billy, E; Vinci, M; Petrini, S; Marampon, F; Quintarelli, C; Taulli, R; Roma, J; Gallego, S; Camero, S; Mariottini, P; Cervelli, M; Maestro, R; Miele, L; De Angelis, B; Locatelli, F; Rota, R | Articolo su rivista | |
| 1-gen-2015 | MicroRNA-101 is repressed by EZH2 and its restoration inhibits tumorigenic features in embryonal rhabdomyosarcoma | Vella, S; Pomella, S; Leoncini, Pp; Colletti, M; Conti, B; Marquez, Ve; Strillacci, A; Roma, J; Gallego, S; Milano, Gm; Capogrossi, Mc; Bertaina, A; Ciarapica, R; Rota, R | Articolo su rivista | |
| 1-gen-2020 | Miswired Enhancer Logic Drives a Cancer of the Muscle Lineage | Gryder, Be; Wachtel, M; Chang, K; El Demerdash, O; Aboreden, Ng; Mohammed, W; Ewert, W; Pomella, S; Rota, R; Wei, Js; Song, Y; Stanton, Bz; Schafer, B; Vakoc, Cr; Khan, J | Articolo su rivista | |
| 1-gen-2021 | MS-275 (Entinostat) Promotes Radio-Sensitivity in PAX3-FOXO1 Rhabdomyosarcoma Cells | Cassandri, M; Pomella, S; Rossetti, A; Petragnano, F; Milazzo, L; Vulcano, F; Camero, S; Codenotti, S; Cicchetti, F; Maggio, R; Festuccia, C; Luca Gravina, G; Fanzani, A; Megiorni, F; Catanoso, M; Marchese, C; Tombolini, V; Locatelli, F; Rota, R; Marampon, F | Articolo su rivista | |
| 15-dic-2023 | MYOD-SKP2 axis boosts tumorigenesis in fusion negative rhabdomyosarcoma by preventing differentiation through p57Kip2 targeting | Pomella, S; Cassandri, M; D'Archivio, L; Porrazzo, A; Cossetti, C; Phelps, D; Perrone, C; Pezzella, M; Cardinale, A; Wachtel, M; Aloisi, S; Milewski, D; Colletti, M; Sreenivas, P; Walters, Zs; Barillari, G; Di Giannatale, A; Milano, Gm; De Stefanis, C; Alaggio, R; Rodriguez-Rodriguez, S; Carlesso, N; Vakoc, Cr; Velardi, E; Schafer, Bw; Guccione, E; Gatz, Sa; Wasti, A; Yohe, M; Ignatius, M; Quintarelli, C; Shipley, J; Miele, L; Khan, J; Houghton, Pj; Marampon, F; Gryder, Be; De Angelis, B; Locatelli, F; Rota, R | Articolo su rivista | |
| 1-gen-2022 | New Insights on the Nuclear Functions and Targeting of FAK in Cancer | Pomella, S; Cassandri, M; Rita Braghini, M; Marampon, F; Alisi, A; R, R | Articolo su rivista | |
| 1-gen-2017 | PAX3-FOXO1 establishes myogenic super enhancers and confers BET bromodomain vulnerability | Gryder, Be; Yohe, Me; Chou, H-; Zhang, X; Marques, J; Wachtel, M; Schaefer, B; Sen, N; Song, Y; Gualtieri, A; Pomella, S; Rota, R; Cleveland, A; Wen, X; Sindiri, S; Wei, Js; Barr, Fg; Das, S; Andresson, T; Guha, R; Lal-Nag, M; Ferrer, M; Shern, Jf; Zhao, K; Thomas, Cj; Khan, J | Articolo su rivista |