Epigenetic alterations and genetic variations of angiotensin-converting enzyme 2 (ACE2) as a functional receptor for SARS-CoV-2: potential clinical implications

Receptor recognition is a crucial step in viral infection and is a critical factor for cell entry and tissue tropism. In several recent studies, angiotensin-converting enzyme 2 (ACE2) has been demonstrated to be the cellular receptor of SARS-CoV-2 as it was previously well known as the receptor of SARS-CoV. SARS-CoV-2 can bind with high affinity to human ACE2 and engages it as an entry receptor. It seems that the genetic, notably epigenetic variations of ACE2 are less known in different popul...

Serendipità: troppa o troppo poca? Note sul sapere dell’antropologia tra baldanza metodologica e pusillanimità teoretica

"Serendipità: troppa o troppo poca? Note sul sapere dell’antropologia tra baldanza metodologica e pusillanimità teoretica" esplora il ruolo della serendipità nella ricerca antropologica. Pietro Vereni riflette su come la serendipità, intesa come capacità di identificare connessioni significative tra eventi apparentemente non correlati, possa arricchire il lavoro etnografico e teorico. Tuttavia, critica anche la "pusillanimità teoretica" che limita l'audacia epistemologica, impedendo agli antr...

I valori dell’Unione nei giudizi nazionali: Stato di diritto e rinvio pregiudiziale

It is well known that quite a number of the cases which have called upon the Court of Justice to rule on the respect of the judges’ independence and impartiality have come to the Court through references for a preliminary ruling pursuant Article 267 TFEU. If we only refer to the cases which have been decided by the Court up until now, we are talking of more than 20 cases on which the Court ruled in an interval between 2019 and 2023. One is allowed to remark that the preliminary ruling mecha...

Contratto e regolazione del mercato