Patients with the metabolic syndrome (MetS) have impaired insulin-induced enhancement of vasodilator responses. The incretin hormone glucagon-like peptide 1 (GLP-1), beyond its effects on blood glucose, has beneficial actions on vascular function. This study, therefore, aimed to assess whether GLP-1 affects insulin-stimulated vasodilator reactivity in patients with the MetS.

Tesauro, M., Schinzari, F., Adamo, A., Rovella, V., Martini, F., Mores, N., et al. (2013). Effects of GLP-1 on forearm vasodilator function and glucose disposal during hyperinsulinemia in the metabolic syndrome. DIABETES CARE, 36(3), 683-689 [10.2337/dc12-0763].

Effects of GLP-1 on forearm vasodilator function and glucose disposal during hyperinsulinemia in the metabolic syndrome

TESAURO, MANFREDI;Rovella, V;LAURO, DAVIDE;
2013-03-01

Abstract

Patients with the metabolic syndrome (MetS) have impaired insulin-induced enhancement of vasodilator responses. The incretin hormone glucagon-like peptide 1 (GLP-1), beyond its effects on blood glucose, has beneficial actions on vascular function. This study, therefore, aimed to assess whether GLP-1 affects insulin-stimulated vasodilator reactivity in patients with the MetS.
mar-2013
Pubblicato
Rilevanza internazionale
Articolo
Esperti anonimi
Settore MED/13 - ENDOCRINOLOGIA
Settore MED/09 - MEDICINA INTERNA
English
Con Impact Factor ISI
Hyperinsulinism; Metabolic Syndrome X; Vasodilation; Humans; Oxidative Stress; Nitroprusside; Glucose; Acetylcholine; Glucagon-Like Peptide 1
Tesauro, M., Schinzari, F., Adamo, A., Rovella, V., Martini, F., Mores, N., et al. (2013). Effects of GLP-1 on forearm vasodilator function and glucose disposal during hyperinsulinemia in the metabolic syndrome. DIABETES CARE, 36(3), 683-689 [10.2337/dc12-0763].
Tesauro, M; Schinzari, F; Adamo, A; Rovella, V; Martini, F; Mores, N; Barini, A; Pitocco, D; Ghirlanda, G; Lauro, D; Campia, U; Cardillo, C
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/79194
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