A total of 550 oral streptococci: 270 Streptococcus mitis, 110 Streptococcus sanguis, 90 Streptococcus anginosus, 50 Streptococcus mutans, 30 Streptococcus salivarius, were isolated from dental plaque and gengival crevices of patients and tested for their susceptibility to 12 β-lactam antibiotics and to 5 non-β-lactam antibiotics, using the microdiluition method. Overall, a reduced susceptibility to penicillin was recorded in 13.4% of cases. The percentage of strains resistant to penicillin appeared significantly higher in S. mitis (24%) than in S. sanguis (19%), in S. mutans (14%) and in S. salivarius (10%). No levels of penicillin resistance were shown by 90 strains of S. anginosus. In susceptibility test to antibiotics, imipenem was the most active molecule tested, confirming its general good activity against oral streptococci. Also third generation cephalosporins such as ceftriaxone and fourth generation cephalosporins such as cefepime, showed good activity. Chinolones, glycopeptides and rifampicin confirmed a good activity against oral streptococci.

Pasquantonio, G., Condò, S., Cerroni, L., Bikiqu, L., Nicoletti, M., Prenna, M., et al. (2012). Antibacterial activity of various antibiotics against oral streptococci isolated in the oral cavity. INTERNATIONAL JOURNAL OF IMMUNOPATHOLOGY AND PHARMACOLOGY, 25(3), 805-809.

Antibacterial activity of various antibiotics against oral streptococci isolated in the oral cavity

Pasquantonio, G;Condò, S;Cerroni, L;
2012-01-01

Abstract

A total of 550 oral streptococci: 270 Streptococcus mitis, 110 Streptococcus sanguis, 90 Streptococcus anginosus, 50 Streptococcus mutans, 30 Streptococcus salivarius, were isolated from dental plaque and gengival crevices of patients and tested for their susceptibility to 12 β-lactam antibiotics and to 5 non-β-lactam antibiotics, using the microdiluition method. Overall, a reduced susceptibility to penicillin was recorded in 13.4% of cases. The percentage of strains resistant to penicillin appeared significantly higher in S. mitis (24%) than in S. sanguis (19%), in S. mutans (14%) and in S. salivarius (10%). No levels of penicillin resistance were shown by 90 strains of S. anginosus. In susceptibility test to antibiotics, imipenem was the most active molecule tested, confirming its general good activity against oral streptococci. Also third generation cephalosporins such as ceftriaxone and fourth generation cephalosporins such as cefepime, showed good activity. Chinolones, glycopeptides and rifampicin confirmed a good activity against oral streptococci.
2012
Pubblicato
Rilevanza internazionale
Articolo
Esperti anonimi
Settore MED/28 - MALATTIE ODONTOSTOMATOLOGICHE
English
Con Impact Factor ISI
Streptococcus; beta-Lactams; Drug Resistance, Bacterial; Humans; Gingiva; Aged; Anti-Bacterial Agents; Endocarditis, Bacterial; beta-Lactam Resistance; Adult; Middle Aged; Mouth; Microbial Sensitivity Tests; Dental Plaque; Female; Male
Pasquantonio, G., Condò, S., Cerroni, L., Bikiqu, L., Nicoletti, M., Prenna, M., et al. (2012). Antibacterial activity of various antibiotics against oral streptococci isolated in the oral cavity. INTERNATIONAL JOURNAL OF IMMUNOPATHOLOGY AND PHARMACOLOGY, 25(3), 805-809.
Pasquantonio, G; Condò, S; Cerroni, L; Bikiqu, L; Nicoletti, M; Prenna, M; Ripa, S
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/78511
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