An experimental study was undertaken to assess aztreonam biliary concentrations in bile duct ligated jaundiced rats. The study proved that aztreonam biliary concentrations are sufficient to inhibit Gram-negative bacteria within the first and the second hour after antibiotic administration. The experimental model suggests that clinical conditions such as lithiasis or neoplasms of the biliary tree should not totally inhibit the antibiotic excretion.

Rulli, F., GALLINELLA MUZI, M., Zanella, E., Cipriani, P., Magni, A., Giordano, A., et al. (1991). Aztreonam biliary excretion in bile duct ligated jaundiced rats. JOURNAL OF CHEMOTHERAPY, 3(2), 98-100.

Aztreonam biliary excretion in bile duct ligated jaundiced rats

RULLI, FRANCESCO;GALLINELLA MUZI, MARCO;ZANELLA, EVERARDO;
1991-04-01

Abstract

An experimental study was undertaken to assess aztreonam biliary concentrations in bile duct ligated jaundiced rats. The study proved that aztreonam biliary concentrations are sufficient to inhibit Gram-negative bacteria within the first and the second hour after antibiotic administration. The experimental model suggests that clinical conditions such as lithiasis or neoplasms of the biliary tree should not totally inhibit the antibiotic excretion.
apr-1991
Pubblicato
Rilevanza nazionale
Articolo
Esperti anonimi
Settore MED/18 - CHIRURGIA GENERALE
English
Rats, Inbred Strains; Rats; Aztreonam; Animals; Cholestasis, Extrahepatic; Bile Ducts; Bile; Ligation; Male
Rulli, F., GALLINELLA MUZI, M., Zanella, E., Cipriani, P., Magni, A., Giordano, A., et al. (1991). Aztreonam biliary excretion in bile duct ligated jaundiced rats. JOURNAL OF CHEMOTHERAPY, 3(2), 98-100.
Rulli, F; GALLINELLA MUZI, M; Zanella, E; Cipriani, P; Magni, A; Giordano, A; Filadoro, F
Articolo su rivista
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/72392
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