Pleural effusion is a common diagnostic problem and a challenge to the thoracic surgeon. The analysis of serum and body fluids for tumor markers is an established diagnostic procedure. Among various markers, tumors are linked to the overexpression of a glycolytic isoenzyme, M2-pyruvate-kinase (M2-PK). This preliminary study evaluated this enzyme as a tumor marker to differentiate malignant from benign pleural effusion.

Elia, S., Massoud, R., Guggino, G., Cristino, B., Cortese, C., De Massimi, A., et al. (2008). Tumor type M2-pyruvate-kinase levels in pleural fluid versus plasma in cancer patients: a further tool to define the need for invasive procedures. EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY, 33(4), 723-727 [10.1016/j.ejcts.2008.01.014].

Tumor type M2-pyruvate-kinase levels in pleural fluid versus plasma in cancer patients: a further tool to define the need for invasive procedures

ELIA, STEFANO;MASSOUD, RENATO;CRISTINO, BENEDETTO;CORTESE, CLAUDIO;ZENOBI, ROSSELLA
2008-04-01

Abstract

Pleural effusion is a common diagnostic problem and a challenge to the thoracic surgeon. The analysis of serum and body fluids for tumor markers is an established diagnostic procedure. Among various markers, tumors are linked to the overexpression of a glycolytic isoenzyme, M2-pyruvate-kinase (M2-PK). This preliminary study evaluated this enzyme as a tumor marker to differentiate malignant from benign pleural effusion.
apr-2008
Pubblicato
Rilevanza internazionale
Articolo
Sì, ma tipo non specificato
Settore BIO/12 - BIOCHIMICA CLINICA E BIOLOGIA MOLECOLARE CLINICA
Settore MED/21 - CHIRURGIA TORACICA
English
Con Impact Factor ISI
Thoracic Neoplasms; Body Fluids; Sensitivity and Specificity; Diagnosis, Differential; Humans; Pyruvate Kinase; Aged; Pleural Effusion, Malignant; Clinical Enzyme Tests; Adult; Enzyme-Linked Immunosorbent Assay; Middle Aged; Tumor Markers, Biological; Female; Male
Elia, S., Massoud, R., Guggino, G., Cristino, B., Cortese, C., De Massimi, A., et al. (2008). Tumor type M2-pyruvate-kinase levels in pleural fluid versus plasma in cancer patients: a further tool to define the need for invasive procedures. EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY, 33(4), 723-727 [10.1016/j.ejcts.2008.01.014].
Elia, S; Massoud, R; Guggino, G; Cristino, B; Cortese, C; De Massimi, A; Zenobi, R
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/59469
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