Punctate porokeratotic keratoderma (PPK) represents a diffuse involvement of palms and soles by multiple, accuminate keratotic papules and plugs, histologically identified by parakeratotic cornoid lamellae. A possible association between PPK and internal malignancy has been previously noted by Herman in 1973. A patient with a 3-month history of PPK is described in which a bronchial carcinoma was recently diagnosed. This association led us to speculate that PPK could be a sign of internal neoplasia, as already established for other forms of palmoplantar keratoderma. We suggest that the presence of an underlying malignancy must be screened for when a diagnosis of PPK is proposed.

Bianchi, L., Orlandi, A., Iraci, S., Spagnoli, L., Nini, G. (1994). Punctate porokeratotic keratoderma - Its occurrence with internal neoplasia. CLINICAL AND EXPERIMENTAL DERMATOLOGY, 19(2), 139-141 [10.1111/j.1365-2230.1994.tb01142.x].

Punctate porokeratotic keratoderma - Its occurrence with internal neoplasia

BIANCHI, LUCA;ORLANDI, AUGUSTO;
1994-01-01

Abstract

Punctate porokeratotic keratoderma (PPK) represents a diffuse involvement of palms and soles by multiple, accuminate keratotic papules and plugs, histologically identified by parakeratotic cornoid lamellae. A possible association between PPK and internal malignancy has been previously noted by Herman in 1973. A patient with a 3-month history of PPK is described in which a bronchial carcinoma was recently diagnosed. This association led us to speculate that PPK could be a sign of internal neoplasia, as already established for other forms of palmoplantar keratoderma. We suggest that the presence of an underlying malignancy must be screened for when a diagnosis of PPK is proposed.
1994
Pubblicato
Rilevanza internazionale
Articolo
Sì, ma tipo non specificato
Settore MED/35 - MALATTIE CUTANEE E VENEREE
English
Con Impact Factor ISI
adult; article; case report; female; human; human tissue; keratoderma; porokeratosis; priority journal; skin tumor; Bronchial Neoplasms; Case Report; Human; Keratoderma, Palmoplantar; Male; Middle Age; Porokeratosis; Skin
Bianchi, L., Orlandi, A., Iraci, S., Spagnoli, L., Nini, G. (1994). Punctate porokeratotic keratoderma - Its occurrence with internal neoplasia. CLINICAL AND EXPERIMENTAL DERMATOLOGY, 19(2), 139-141 [10.1111/j.1365-2230.1994.tb01142.x].
Bianchi, L; Orlandi, A; Iraci, S; Spagnoli, L; Nini, G
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/57377
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