Central venous access is necessary in patients candidate for peripheral blood stem cell (PBSC) collection. We report our experience with a dual lumen femoral catheter (Gamcath, 11 french), initially designed for hemodialysis. We studied 147 patients and performed 488 collections after mobilization with either G-CSF alone or chemotherapy + G-CSF, when the white blood cell count exceeded 1 x 10(9)/L, or when a measurable population of CD34+ cells (20/microL) was detected in peripheral blood. All patients received systemic anticoagulation with a low weight heparin and ultrasound examination was performed after the removal of the catheter. Seven patients developed thrombosis (4.7%), ten experienced hematomas at the site of catheter placement (6.8%) despite prophylactic platelet transfusions, while only one patient (0.6%) had a catheter-related infection. In conclusion, the short-term use of large bore femoral catheters in setting up PBSC collection seems to be associated with minimal risk of infection and low thrombotic incidence.

Adorno, G., Zinno, F., Bruno, A., Lanti, A., Ballatore, G., Masi, M., et al. (1999). Femoral catheters: safety and efficacy in peripheral blood stem cell collection. INTERNATIONAL JOURNAL OF ARTIFICIAL ORGANS, 22(10), 710-2.

Femoral catheters: safety and efficacy in peripheral blood stem cell collection

ADORNO, GASPARE;ZINNO, FRANCESCO;CUDILLO, LAURA;DEL POETA, GIOVANNI;DEL PRINCIPE, MARIA ILARIA;MOROSETTI, MASSIMO;
1999-10-01

Abstract

Central venous access is necessary in patients candidate for peripheral blood stem cell (PBSC) collection. We report our experience with a dual lumen femoral catheter (Gamcath, 11 french), initially designed for hemodialysis. We studied 147 patients and performed 488 collections after mobilization with either G-CSF alone or chemotherapy + G-CSF, when the white blood cell count exceeded 1 x 10(9)/L, or when a measurable population of CD34+ cells (20/microL) was detected in peripheral blood. All patients received systemic anticoagulation with a low weight heparin and ultrasound examination was performed after the removal of the catheter. Seven patients developed thrombosis (4.7%), ten experienced hematomas at the site of catheter placement (6.8%) despite prophylactic platelet transfusions, while only one patient (0.6%) had a catheter-related infection. In conclusion, the short-term use of large bore femoral catheters in setting up PBSC collection seems to be associated with minimal risk of infection and low thrombotic incidence.
ott-1999
Pubblicato
Rilevanza internazionale
Articolo
Sì, ma tipo non specificato
Settore MED/05 - PATOLOGIA CLINICA
English
Con Impact Factor ISI
Sensitivity and Specificity; Equipment Safety; Male; Catheterization, Peripheral; Hematopoietic Stem Cell Transplantation; Transplantation, Autologous; Female; Hematopoietic Stem Cell Mobilization; Humans; Polyurethanes; Femoral Vein; Hematologic Neoplasms; Venous Thrombosis
Adorno, G., Zinno, F., Bruno, A., Lanti, A., Ballatore, G., Masi, M., et al. (1999). Femoral catheters: safety and efficacy in peripheral blood stem cell collection. INTERNATIONAL JOURNAL OF ARTIFICIAL ORGANS, 22(10), 710-2.
Adorno, G; Zinno, F; Bruno, A; Lanti, A; Ballatore, G; Masi, M; Cudillo, L; DEL POETA, G; Riccitelli, A; DEL PRINCIPE, Mi; Pepe, R; Marchitelli, E; Morosetti, M; Meloni, C; Isacchi, G; Amadori, S
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/56370
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