PR8 virus depressed interleukin-2 (IL-2) and natural killer (NK) cell activity in BALB/c infected mice. IL-2 production was not dependent on (i) a decreased number of T cells or (ii) a primary defect in IL-1 production, but on a T-suppressor cell subpopulation. In fact, when T suppressor cells were removed from infected spleen cells, we observed normal levels of IL-2 activity.
DEL GOBBO, V., Villani, N., Marini, S., Balestra, E., Calio, R. (1990). Suppressor cells induced by influenza virus inhibit interleukin-2 production in mice. IMMUNOLOGY, 69(3), 454-459.
Suppressor cells induced by influenza virus inhibit interleukin-2 production in mice
DEL GOBBO, VERA;MARINI, STEFANO;BALESTRA, EMANUELA;
1990-01-01
Abstract
PR8 virus depressed interleukin-2 (IL-2) and natural killer (NK) cell activity in BALB/c infected mice. IL-2 production was not dependent on (i) a decreased number of T cells or (ii) a primary defect in IL-1 production, but on a T-suppressor cell subpopulation. In fact, when T suppressor cells were removed from infected spleen cells, we observed normal levels of IL-2 activity.File in questo prodotto:
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