A polymorphism in the interleukin 12B gene was recently reported to be strongly associated with type 1 diabetes in 422 Australian and British families. We analyzed the same polymorphism in 470 Italian type 1 diabetic patients and 544 matched control subjects and found no evidence of association with the disease.

Nistico, L., Giorgi, G., Giordano, M., Galgani, A., Petrone, A., D'Alfonso, S., et al. (2002). IL12B polymorphism and type 1 diabetes in the Italian population: A case-control study. DIABETES, 51(5), 1649-1650.

IL12B polymorphism and type 1 diabetes in the Italian population: A case-control study

FEDERICI, MASSIMO;
2002-01-01

Abstract

A polymorphism in the interleukin 12B gene was recently reported to be strongly associated with type 1 diabetes in 422 Australian and British families. We analyzed the same polymorphism in 470 Italian type 1 diabetic patients and 544 matched control subjects and found no evidence of association with the disease.
2002
Pubblicato
Rilevanza internazionale
Articolo
Sì, ma tipo non specificato
Settore M-EDF/01 - METODI E DIDATTICHE DELLE ATTIVITA' MOTORIE
Settore MED/09 - MEDICINA INTERNA
English
Con Impact Factor ISI
interleukin 12; allele; article; clinical feature; controlled study; disease course; female; gene frequency; genetic association; genetic epidemiology; genetic polymorphism; genetic predisposition; genetic risk; genotype; human; insulin dependent diabetes mellitus; Italy; major clinical study; male; onset age; phenotype; priority journal; risk assessment; school child; Adolescent; Adult; Case-Control Studies; Child; Diabetes Mellitus, Type 1; Female; Gene Frequency; Genetic Predisposition to Disease; Haplotypes; Humans; Interleukin-12; Italy; Male; Polymorphism, Genetic; Risk Factors
Nistico, L., Giorgi, G., Giordano, M., Galgani, A., Petrone, A., D'Alfonso, S., et al. (2002). IL12B polymorphism and type 1 diabetes in the Italian population: A case-control study. DIABETES, 51(5), 1649-1650.
Nistico, L; Giorgi, G; Giordano, M; Galgani, A; Petrone, A; D'Alfonso, S; Federici, M; Di Mario, U; Pozzilli, P; Buzzetti, R; Cascino, I
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/53051
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