Activating mutations in the K-ras oncogene mainly occur in codons 12 and 13 and may be predictive of response to drugs directly linked to the K-ras signaling pathway, such as panitumumab and cetuximab.

Palmirotta, R., Savonarola, A., Formica, V., Ludovici, G., Del Monte, G., Roselli, M., et al. (2009). A novel K-ras mutation in colorectal cancer. A case report and literature review. ANTICANCER RESEARCH, 29(8), 3369-3374.

A novel K-ras mutation in colorectal cancer. A case report and literature review

Formica, V;ROSELLI, MARIO;
2009-08-01

Abstract

Activating mutations in the K-ras oncogene mainly occur in codons 12 and 13 and may be predictive of response to drugs directly linked to the K-ras signaling pathway, such as panitumumab and cetuximab.
ago-2009
Pubblicato
Rilevanza internazionale
Articolo
Sì, ma tipo non specificato
Settore MED/06 - ONCOLOGIA MEDICA
English
Con Impact Factor ISI
Camptothecin; Tumor Suppressor Protein p53; Colorectal Neoplasms; Female; Fluorouracil; Immunoenzyme Techniques; Humans; Leucovorin; Organoplatinum Compounds; Receptor, Epidermal Growth Factor; Proto-Oncogene Proteins B-raf; Antineoplastic Combined Chemotherapy Protocols; Proto-Oncogene Proteins; ras Proteins; Adenocarcinoma, Mucinous; Adult; Antibodies, Monoclonal
Palmirotta, R., Savonarola, A., Formica, V., Ludovici, G., Del Monte, G., Roselli, M., et al. (2009). A novel K-ras mutation in colorectal cancer. A case report and literature review. ANTICANCER RESEARCH, 29(8), 3369-3374.
Palmirotta, R; Savonarola, A; Formica, V; Ludovici, G; Del Monte, G; Roselli, M; Guadagni, F
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2108/47451
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